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Scarf2 Gene Detail
Summary
  • Symbol
    Scarf2
  • Name
    scavenger receptor class F, member 2
  • Synonyms
    Srec2, SREC-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858430
    NCBI Gene: 224024
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17615146-17626157 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 11.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858430
 protein coding gene Chr16:17615146-17626158 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022591
 protein coding gene Chr16:14978431-14990686 (+)
A/J MGP_AJ_G0022552
 protein coding gene Chr16:14232580-14243586 (+)
AKR/J MGP_AKRJ_G0022529
 protein coding gene Chr16:14787233-14798182 (+)
BALB/cJ MGP_BALBcJ_G0022555
 protein coding gene Chr16:14384304-14395265 (+)
C3H/HeJ MGP_C3HHeJ_G0022322
 protein coding gene Chr16:14932364-14943267 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023006
 protein coding gene Chr16:15208715-15219631 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020526
 protein coding gene Chr16:14289716-14300691 (+)
CAST/EiJ MGP_CASTEiJ_G0021850
 protein coding gene Chr16:14856057-14867010 (+)
CBA/J MGP_CBAJ_G0022293
 protein coding gene Chr16:15887520-15898441 (+)
DBA/2J MGP_DBA2J_G0022423
 protein coding gene Chr16:14144793-14155979 (+)
FVB/NJ MGP_FVBNJ_G0022399
 protein coding gene Chr16:14192160-14203080 (+)
LP/J MGP_LPJ_G0022490
 protein coding gene Chr16:14748139-14759070 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022420
 protein coding gene Chr16:15574376-15586993 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023017
 protein coding gene Chr16:14732182-14744302 (+)
PWK/PhJ MGP_PWKPhJ_G0021593
 protein coding gene Chr16:14404816-14416274 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021421
 protein coding gene Chr16:14704381-14715313 (+)
WSB/EiJ MGP_WSBEiJ_G0021897
 protein coding gene Chr16:14717839-14730292 (+)



Homology
more
  • Human Ortholog
    SCARF2, scavenger receptor class F member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCARF2, scavenger receptor class F member 2
  • Synonyms
    NSR1, SREC2, SREC-II, SRECRP-1, VDEGS
  • Links
    NCBI Gene ID: 91179
    UniProt: Q96GP6

  • Chr Location
    22q11.21; chr22:20424584-20437826 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SCARF2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    9
  • cDNA Data
    68
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000012017 Ensembl Gene Model | MGI Sequence Detail 11012 C57BL/6J ±  kb
    transcript ENSMUST00000012161 Ensembl | MGI Sequence Detail 3308 Not Applicable  
    polypeptide ENSMUSP00000012161 Ensembl | MGI Sequence Detail 833 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 70
      Genomic 2
      cDNA 68

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1858437, MGI:1858438, MGI:2146384
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 2
      Phenotypes 11
    • Earliest
      J:60871 Lund J, et al., Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2. Genomics. 2000 Feb 1;63(3):374-83
    • Latest
      J:359574 Eom TY, et al., Tbx1 haploinsufficiency leads to local skull deformity, paraflocculus and flocculus dysplasia, and motor-learning deficit in 22q11.2 deletion syndrome. Nat Commun. 2024 Dec 5;15(1):10510
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    03/25/2025
    MGI 6.24     		The Jackson Laboratory