About   Help   FAQ
Rgs11 Gene Detail
Summary
  • Symbol
    Rgs11
  • Name
    regulator of G-protein signaling 11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354739
    NCBI Gene: 50782
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26421925-26430298 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.07 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    338 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354739
 protein coding gene Chr17:26421500-26430298 (+)
129S1/SvImJ ENSMUSG00200053420
 protein coding gene Chr17:21867413-21875918 (+)
A/J ENSMUSG00195054277
 protein coding gene Chr17:22894617-22902973 (+)
AKR/J ENSMUSG00220053191
 protein coding gene Chr17:21931481-21939829 (+)
BALB/cJ ENSMUSG00180040793
 protein coding gene Chr17:22165554-22173903 (+)
C3H/HeJ ENSMUSG00175052395
 protein coding gene Chr17:21923672-21932174 (+)
C57BL/6NJ ENSMUSG00215051879
 protein coding gene Chr17:21931553-21939919 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021277
 protein coding gene Chr17:22053171-22061563 (+)
CAST/EiJ ENSTCUG00005041525
 protein coding gene Chr17:22523961-22532198 (+)
CBA/J ENSMUSG00210049832
 protein coding gene Chr17:21762616-21770963 (+)
DBA/2J ENSMUSG00185052905
 protein coding gene Chr17:23982843-23991167 (+)
FVB/NJ ENSMUSG00205045604
 protein coding gene Chr17:22238488-22246987 (+)
JF1/MsJ ENSUMUG00000051719
 protein coding gene Chr17:23428491-23437013 (+)
LP/J ENSMUSG00230054943
 protein coding gene Chr17:25371932-25380434 (+)
NOD/ShiLtJ ENSMUSG00190043991
 protein coding gene Chr17:21871562-21879912 (+)
NZO/HlLtJ ENSMUSG00225050932
 protein coding gene Chr17:27301813-27310316 (+)
PWK/PhJ ENSLUMG00010032677
 protein coding gene Chr17:21340761-21349112 (+)
SPRET/EiJ ENSMSPG00010048178
 protein coding gene Chr17:22673543-22681711 (+)
WSB/EiJ ENSIUOG00005051017
 protein coding gene Chr17:22603780-22612314 (+)



Homology
more
  • Human Ortholog
    RGS11, regulator of G protein signaling 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RGS11, regulator of G protein signaling 11
  • Synonyms
    RS11
  • Links
    NCBI Gene ID: 8786
    UniProt: O94810

  • Chr Location
    16p13.3; chr16:268301-275980 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    1 images
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit abnormal cone and rod b-wave electrophysiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    35
  • cDNA Data
    46
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024186 Ensembl Gene Model | MGI Sequence Detail 8374 C57BL/6J ±  kb
transcript ENSMUST00000025020 Ensembl | MGI Sequence Detail 2006 Not Applicable  
polypeptide ENSMUSP00000025020 Ensembl | MGI Sequence Detail 466 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 46
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147122
References
more
  • Summaries
    All 59
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 20
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:374580 Hong W, et al., Kruppel-like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex. Brain Pathol. 2023 Sep;33(5):e13186
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory