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Rps26 Gene Detail
Summary
  • Symbol
    Rps26
  • Name
    ribosomal protein S26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351628
    NCBI Gene: 27370
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128460398-128462375 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 77.11 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351628
 protein coding gene Chr10:128460398-128462616 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017874
 protein coding gene Chr10:132383084-132385060 (-)
A/J MGP_AJ_G0017849
 protein coding gene Chr10:127066565-127074045 (-)
AKR/J MGP_AKRJ_G0017812
 protein coding gene Chr10:130784895-130786985 (-)
BALB/cJ MGP_BALBcJ_G0017813
 protein coding gene Chr10:127439654-127441630 (-)
C3H/HeJ MGP_C3HHeJ_G0017636
 protein coding gene Chr10:130950889-130953694 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018268
 protein coding gene Chr10:136862062-136864085 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015946
 protein coding gene Chr10:120987602-120989348 (-)
CAST/EiJ MGP_CASTEiJ_G0017197
 protein coding gene Chr10:131673214-131677103 (-)
CBA/J MGP_CBAJ_G0017606
 protein coding gene Chr10:142436861-142441041 (-)
DBA/2J MGP_DBA2J_G0017712
 protein coding gene Chr10:126117417-126125234 (-)
FVB/NJ MGP_FVBNJ_G0017707
 protein coding gene Chr10:125047173-125049149 (-)
LP/J MGP_LPJ_G0017786
 protein coding gene Chr10:132980123-132982100 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0018308
 protein coding gene Chr10:130889279-130891255 (-)
PWK/PhJ MGP_PWKPhJ_G0016982
 protein coding gene Chr10:126387073-126389164 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016771
 protein coding gene Chr10:130003368-130006176 (-)
WSB/EiJ MGP_WSBEiJ_G0017256
 protein coding gene Chr10:131110781-131112758 (-)



Homology
more
  • Human Ortholog
    RPS26, ribosomal protein S26
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS26, ribosomal protein S26
  • Synonyms
    DBA10, eS26, S26
  • Links
    NCBI Gene ID: 6231
    neXtProt AC: NX_P62854
    UniProt: P62854

  • Chr Location
    12q13.2; chr12:56041351-56044697 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RPS26 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Knockout in mouse oocytes results in arrested follicle development from pre-antral follicles to antral follicles and all oocytes die by P84 resulting in premature ovarian failure.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    16
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 27370 NCBI Gene Model | MGI Sequence Detail 1978 C57BL/6J ±  kb
    transcript NM_013765 RefSeq | MGI Sequence Detail 457 C57BL/6  
    polypeptide P62855 UniProt | EBI | MGI Sequence Detail 115 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 16
      Primer pair 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 4
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory