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Tinag Gene Detail
Summary
  • Symbol
    Tinag
  • Name
    tubulointerstitial nephritis antigen
  • Synonyms
    TIN-ag
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349477
    NCBI Gene: 26944
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:76858975-76953076 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 42.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    265 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349477
protein coding gene Chr9:76858975-76953084 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035050
protein coding gene Chr9:77361772-77454192 (-)
A/J MGP_AJ_G0035031
protein coding gene Chr9:74654081-74749301 (-)
AKR/J MGP_AKRJ_G0034960
protein coding gene Chr9:76429907-76527056 (-)
BALB/cJ MGP_BALBcJ_G0035023
protein coding gene Chr9:74337382-74430762 (-)
C3H/HeJ MGP_C3HHeJ_G0034732
protein coding gene Chr9:76925380-77027056 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035541
protein coding gene Chr9:79423704-79517246 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032452
protein coding gene Chr9:73944401-74033818 (-)
CAST/EiJ MGP_CASTEiJ_G0034054
protein coding gene Chr9:77276538-77379853 (-)
CBA/J MGP_CBAJ_G0034704
protein coding gene Chr9:82167471-82269363 (-)
DBA/2J MGP_DBA2J_G0034864
protein coding gene Chr9:74320332-74412345 (-)
FVB/NJ MGP_FVBNJ_G0034806
protein coding gene Chr9:73587571-73681240 (-)
LP/J MGP_LPJ_G0034945
protein coding gene Chr9:77589928-77684322 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034847
protein coding gene Chr9:83358215-83470875 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035564
protein coding gene Chr9:76604818-76698666 (-)
PWK/PhJ MGP_PWKPhJ_G0033758
protein coding gene Chr9:74576276-74671950 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033591
protein coding gene Chr9:76850929-76956024 (-)
WSB/EiJ MGP_WSBEiJ_G0034166
protein coding gene Chr9:76528608-76619996 (-)



Homology
more
  • Human Ortholog
    TINAG, tubulointerstitial nephritis antigen
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TINAG, tubulointerstitial nephritis antigen
  • Synonyms
    TIN-AG
  • Links
    NCBI Gene ID: 27283
    neXtProt AC: NX_Q9UJW2
    UniProt: Q9UJW2

  • Chr Location
    6p12.1; chr6:54307859-54390142 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032357 Ensembl Gene Model | MGI Sequence Detail 94102 C57BL/6J ±  kb
transcript ENSMUST00000034911 Ensembl | MGI Sequence Detail 1726 Not Applicable  
polypeptide ENSMUSP00000034911 Ensembl | MGI Sequence Detail 475 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR025661 Cysteine peptidase, asparagine active site
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR013128 Peptidase C1A
    IPR000668 Peptidase C1A, papain C-terminal
    IPR001212 Somatomedin B domain
Molecular
Reagents
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  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
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MGI:2143063
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:237827 Gineste C, et al., In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul Disord. 2013 Apr;23(4):357-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory