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Slc27a4 Gene Detail
Summary
  • Symbol
    Slc27a4
  • Name
    solute carrier family 27 (fatty acid transporter), member 4
  • Synonyms
    FATP4, fatty acid transport protein 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347347
    NCBI Gene: 26569
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:29692646-29707534 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 20.64 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    449 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347347
 protein coding gene Chr2:29692646-29707534 (+)
129S1/SvImJ ENSMUSG00200049423
 protein coding gene Chr2:26662769-26677666 (+)
A/J ENSMUSG00195038001
 protein coding gene Chr2:26756421-26771309 (+)
AKR/J ENSMUSG00220049438
 protein coding gene Chr2:26874960-26889848 (+)
BALB/cJ ENSMUSG00180051971
 protein coding gene Chr2:26775711-26790599 (+)
C3H/HeJ ENSMUSG00175052039
 protein coding gene Chr2:26745028-26759914 (+)
C57BL/6NJ ENSMUSG00215048797
 protein coding gene Chr2:26810699-26825586 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023371
 protein coding gene Chr2:25664049-25678540 (+)
CAST/EiJ ENSTCUG00005052467
 protein coding gene Chr2:26481429-26496321 (+)
CBA/J ENSMUSG00210016669
 protein coding gene Chr2:26778185-26793072 (+)
DBA/2J ENSMUSG00185047155
 protein coding gene Chr2:26670501-26685388 (+)
FVB/NJ ENSMUSG00205046211
 protein coding gene Chr2:26522527-26537415 (+)
JF1/MsJ ENSUMUG00000028609
 protein coding gene Chr2:26566956-26581669 (+)
LP/J ENSMUSG00230038505
 protein coding gene Chr2:28598543-28613441 (+)
NOD/ShiLtJ ENSMUSG00190042458
 protein coding gene Chr2:26777345-26792232 (+)
NZO/HlLtJ ENSMUSG00225007668
 protein coding gene Chr2:36347601-36362491 (+)
PWK/PhJ ENSLUMG00010042804
 protein coding gene Chr2:26644117-26658761 (+)
SPRET/EiJ ENSMSPG00010042662
 protein coding gene Chr2:27366799-27380168 (+)
WSB/EiJ ENSIUOG00005051049
 protein coding gene Chr2:26629264-26644164 (+)



Homology
more
  • Human Ortholog
    SLC27A4, solute carrier family 27 member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC27A4, solute carrier family 27 member 4
  • Synonyms
    ACSVL4, FATP4, IPS
  • Links
    NCBI Gene ID: 10999
    UniProt: Q6P1M0

  • Chr Location
    9q34.11; chr9:128340506-128363283 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Slc27a4 mouse models

Human Disease Mouse Models
      
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    47 phenotypes from 6 alleles in 7 genetic backgrounds
    2 phenotypes from multigenic genotypes
    10 images
    35 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice are not viable. While mice of one mutant line die during early development, mice of other mutant lines die at birth exhibiting abnormal skin.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    78
  • GO References
    24
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    119
  • cDNA Data
    74
  • Literature Summary
    21
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 26569 NCBI Gene Model | MGI Sequence Detail 14889 C57BL/6J ±  kb
    transcript NM_011989 RefSeq | MGI Sequence Detail 4054 ZRU/MplStud  
    polypeptide Q91VE0 UniProt | EBI | MGI Sequence Detail 643 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 81
      Genomic 1
      cDNA 75
      Primer pair 5
      Antibodies 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2139436
    References
    more
    • Summaries
      All 116
      Developmental Gene Expression 21
      Diseases 2
      Gene Ontology 24
      Phenotypes 35
    • Earliest
      J:42634 Hirsch D, et al., A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8625-9
    • Latest
      J:383477 Kim M, et al., Egfl7 regulates embryonic angiogenesis and placental vascular function in mice. Biochem Biophys Res Commun. 2026 Apr 14;819:153770
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory