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Anxa10 Gene Detail
Summary
  • Symbol
    Anxa10
  • Name
    annexin A10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347090
    NCBI Gene: 26359
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:62510076-62576184 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 31.55 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    293 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347090
 protein coding gene Chr8:62510076-62576227 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033638
 protein coding gene Chr8:62014566-62081071 (-)
A/J MGP_AJ_G0033620
 protein coding gene Chr8:59367545-59428606 (-)
AKR/J MGP_AKRJ_G0033545
 protein coding gene Chr8:61086057-61147696 (-)
BALB/cJ MGP_BALBcJ_G0033616
 protein coding gene Chr8:59622468-59687360 (-)
C3H/HeJ MGP_C3HHeJ_G0033326
 protein coding gene Chr8:61753827-61831042 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034133
 protein coding gene Chr8:64342506-64411708 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031081
 protein coding gene Chr8:54589805-54645738 (-)
CAST/EiJ MGP_CASTEiJ_G0032651
 protein coding gene Chr8:61162096-61232409 (-)
CBA/J MGP_CBAJ_G0033304
 protein coding gene Chr8:66711282-66781426 (-)
DBA/2J MGP_DBA2J_G0033458
 protein coding gene Chr8:59114223-59186142 (-)
FVB/NJ MGP_FVBNJ_G0033399
 protein coding gene Chr8:58420684-58483497 (-)
LP/J MGP_LPJ_G0033546
 protein coding gene Chr8:61989440-62057316 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033443
 protein coding gene Chr8:68771762-68846852 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034151
 protein coding gene Chr8:61334912-61397081 (-)
PWK/PhJ MGP_PWKPhJ_G0032360
 protein coding gene Chr8:58429006-58490525 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032196
 protein coding gene Chr8:60270621-60335090 (-)
WSB/EiJ MGP_WSBEiJ_G0032768
 protein coding gene Chr8:61656461-61721198 (-)



Homology
more
  • Human Ortholog
    ANXA10, annexin A10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANXA10, annexin A10
  • Synonyms
    ANX14
  • Links
    NCBI Gene ID: 11199
    neXtProt AC: NX_Q9UJ72
    UniProt: Q9UJ72

  • Chr Location
    4q32.3; chr4:168092537-168187736 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Litter sizes from crosses of females that are either homozygous or heterozygous for a null allele contain fewer pups than wild-type females, indicating a dominant maternal effect on embryonic lethality. Embryos of homozygous null females die between E4.5 and E12.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031635 Ensembl Gene Model | MGI Sequence Detail 66109 C57BL/6J ±  kb
transcript ENSMUST00000034052 Ensembl | MGI Sequence Detail 1763 Not Applicable  
polypeptide ENSMUSP00000034052 Ensembl | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:57244 Morgan RO, et al., Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution. Genomics. 1999 Aug 15;60(1):40-9
  • Latest
    J:344399 Motomura K, et al., Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward beta-Cell Failure. Diabetes. 2024 Jan 1;73(1):75-92
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory