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Psma4 Gene Detail
Summary
  • Symbol
    Psma4
  • Name
    proteasome subunit alpha 4
  • Synonyms
    C9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347060
    NCBI Gene: 26441
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr9:54858074-54865314 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.84 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347060
 protein coding gene Chr9:54858074-54865316 (+)
129S1/SvImJ ENSMUSG00200030537
 protein coding gene Chr9:51985267-51992501 (+)
A/J ENSMUSG00195039811
 protein coding gene Chr9:51683657-51690897 (+)
AKR/J ENSMUSG00220030467
 protein coding gene Chr9:51816580-51823820 (+)
BALB/cJ ENSMUSG00180016262
 protein coding gene Chr9:51797029-51804269 (+)
C3H/HeJ ENSMUSG00175020769
 protein coding gene Chr9:51808817-51816057 (+)
C57BL/6NJ ENSMUSG00215024422
 protein coding gene Chr9:51782168-51789408 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032238
 protein coding gene Chr9:51705499-51712536 (+)
CAST/EiJ ENSTCUG00005020988
 protein coding gene Chr9:51718515-51725748 (+)
CBA/J ENSMUSG00210035354
 protein coding gene Chr9:51911757-51918991 (+)
DBA/2J ENSMUSG00185038457
 protein coding gene Chr9:51941212-51948446 (+)
FVB/NJ ENSMUSG00205034273
 protein coding gene Chr9:52221361-52228601 (+)
JF1/MsJ ENSUMUG00000045575
 protein coding gene Chr9:51943800-51951005 (+)
LP/J ENSMUSG00230035067
 protein coding gene Chr9:52185241-52192475 (+)
NOD/ShiLtJ ENSMUSG00190039034
 protein coding gene Chr9:51999177-52006417 (+)
NZO/HlLtJ ENSMUSG00225027841
 protein coding gene Chr9:52206902-52214142 (+)
PWK/PhJ ENSLUMG00010038164
 protein coding gene Chr9:51906685-51914118 (+)
SPRET/EiJ ENSMSPG00010022930
 protein coding gene Chr9:52916144-52923210 (+)
WSB/EiJ ENSIUOG00005037548
 protein coding gene Chr9:51409869-51417105 (+)



Homology
more
  • Human Ortholog
    PSMA4, proteasome 20S subunit alpha 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMA4, proteasome 20S subunit alpha 4
  • Synonyms
    HC9, HsT17706, PSC9
  • Links
    NCBI Gene ID: 5685
    UniProt: P25789

  • Chr Location
    15q25.1; chr15:78540089-78552417 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    45
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    1
  • cDNA Data
    177
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032301 Ensembl Gene Model | MGI Sequence Detail 7241 C57BL/6J ±  kb
transcript ENSMUST00000034848 Ensembl | MGI Sequence Detail 1165 Not Applicable  
polypeptide ENSMUSP00000034848 Ensembl | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 177
    cDNA 177
    Antibodies 1

    Microarray probesets 3
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 4
  • Earliest
    J:57232 Elenich LA, et al., The complete primary structure of mouse 20S proteasomes. Immunogenetics. 1999 Sep;49(10):835-42
  • Latest
    J:354587 Nedomova M, et al., DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. iScience. 2024 Oct 18;27(10):110893
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory