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Calcoco2 Gene Detail
Summary
  • Symbol
    Calcoco2
  • Name
    calcium binding and coiled-coil domain 2
  • Synonyms
    2410154J16Rik, Ndp52, Ndp52l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343177
    NCBI Gene: 76815
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:95990152-96002790 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.40 cM, cytoband C
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343177
 protein coding gene Chr11:95989742-96015362 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018998
 protein coding gene Chr11:98390268-98403094 (-)
A/J MGP_AJ_G0018966
 protein coding gene Chr11:94377953-94390725 (-)
AKR/J MGP_AKRJ_G0018936
 protein coding gene Chr11:97288265-97301202 (-)
BALB/cJ MGP_BALBcJ_G0018939
 protein coding gene Chr11:94863454-94877710 (-)
C3H/HeJ MGP_C3HHeJ_G0018753
 protein coding gene Chr11:97431636-97444196 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019391
 protein coding gene Chr11:101459716-101475480 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017021
 protein coding gene Chr11:91866151-91885273 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0018724
 protein coding gene Chr11:105614497-105627122 (-)
DBA/2J MGP_DBA2J_G0018832
 protein coding gene Chr11:93949377-93963015 (-)
FVB/NJ MGP_FVBNJ_G0018821
 protein coding gene Chr11:93424203-93437234 (-)
LP/J MGP_LPJ_G0018902
 protein coding gene Chr11:98930717-98945750 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018848
 protein coding gene Chr11:105605366-105619320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019431
 protein coding gene Chr11:97591797-97607421 (-)
PWK/PhJ MGP_PWKPhJ_G0018078
 protein coding gene Chr11:94901529-94914114 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017867
 protein coding gene Chr11:97305196-97324073 (-)
WSB/EiJ MGP_WSBEiJ_G0018356
 protein coding gene Chr11:97488753-97500976 (-)



Homology
more
  • Human Ortholog
    CALCOCO2, calcium binding and coiled-coil domain 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALCOCO2, calcium binding and coiled-coil domain 2
  • Synonyms
    NDP52
  • Links
    NCBI Gene ID: 10241
    neXtProt AC: NX_Q13137
    UniProt: Q13137

  • Chr Location
    17q21.32; chr17:48831018-48866522 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006056 Ensembl Gene Model | MGI Sequence Detail 12639 C57BL/6J ±  kb
transcript ENSMUST00000068686 Ensembl | MGI Sequence Detail 1621 Not Applicable  
polypeptide ENSMUSP00000087407 Ensembl | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR041611 SKICH domain
Molecular
Reagents
less
  • All nucleic 22
    Genomic 8
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:1924065, MGI:2144626
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory