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Slc25a17 Gene Detail
Summary
  • Symbol
    Slc25a17
  • Name
    solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
  • Synonyms
    34kDa, PMP34
  • Feature Type
    protein coding gene
  • IDs
    MGI:1342248
    NCBI Gene: 20524
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:81203122-81244966 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1210 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1342248
 protein coding gene Chr15:81203112-81245013 (-)
129S1/SvImJ ENSMUSG00200049863
 protein coding gene Chr15:78309924-78351830 (-)
A/J ENSMUSG00195051335
 protein coding gene Chr15:78246710-78288620 (-)
AKR/J ENSMUSG00220049194
 protein coding gene Chr15:78289901-78331802 (-)
BALB/cJ ENSMUSG00180052730
 protein coding gene Chr15:78123704-78165605 (-)
C3H/HeJ ENSMUSG00175041354
 protein coding gene Chr15:78434745-78476650 (-)
C57BL/6NJ ENSMUSG00215049463
 protein coding gene Chr15:78220019-78261923 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020049
 protein coding gene Chr15:75332283-75376250 (-)
CAST/EiJ ENSTCUG00005043035
 protein coding gene Chr15:77741367-77783989 (-)
CBA/J ENSMUSG00210041304
 protein coding gene Chr15:78209829-78251739 (-)
DBA/2J ENSMUSG00185049691
 protein coding gene Chr15:78233093-78274947 (-)
FVB/NJ ENSMUSG00205025335
 protein coding gene Chr15:77953831-77995612 (-)
JF1/MsJ ENSUMUG00000034308
 protein coding gene Chr15:77806424-77848889 (-)
LP/J ENSMUSG00230051587
 protein coding gene Chr15:81557349-81599251 (-)
NOD/ShiLtJ ENSMUSG00190049538
 protein coding gene Chr15:78226904-78268809 (-)
NZO/HlLtJ ENSMUSG00225048604
 protein coding gene Chr15:81897469-81939244 (-)
PWK/PhJ ENSLUMG00010040365
 protein coding gene Chr15:78027283-78069855 (-)
SPRET/EiJ ENSMSPG00010048799
 protein coding gene Chr15:79674717-79716533 (-)
WSB/EiJ ENSIUOG00005041164
 protein coding gene Chr15:78302351-78344239 (-)



Homology
more
  • Human Ortholog
    SLC25A17, solute carrier family 25 member 17
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A17, solute carrier family 25 member 17
  • Synonyms
    PMP34
  • Links
    NCBI Gene ID: 10478
    UniProt: O43808

  • Chr Location
    22q13.2; chr22:40769630-40819401 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 2 genetic backgrounds
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit background sensitive prenatal lethality and phytol-diet induced enlarged liver, hepatic steatosis, and liver apoptosis, and inflammation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    57
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    23
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20524 NCBI Gene Model | MGI Sequence Detail 41845 C57BL/6J ±  kb
    transcript NM_011399 RefSeq | MGI Sequence Detail 1667 C57BL/6  
    polypeptide O70579 UniProt | EBI | MGI Sequence Detail 307 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000015012 peroxisomal membrane protein PMP34
      (term hierarchy)
    • InterPro Domains
      IPR052217 Mitochondrial and Peroxisomal Carrier Protein
      IPR002067 Mitochondrial carrier protein
      IPR023395 Mitochondrial carrier protein domain superfamily
      IPR018108 Mitochondrial carrier protein, transmembrane region
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 23
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 10
      Phenotypes 29
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory