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Gene Expression Data
Assay Details
Assay
Reference: J:41128 Johnston SH, et al., A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development. 1997 Jun;124(11):2245-54
Assay type: RNA in situ
MGI Accession ID: MGI:1337661
Gene symbol: Lfng
Gene name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Probe: lunatic fringe cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2.A: embryonic day 8.5 (more )
Note: 10-somite stage.
Structure Level Pattern Image Note
TS13: rhombomere 3 Present 2A
TS13: rhombomere 5 Present 2A
TS13: trunk unsegmented mesenchyme Present 2A
TS13: neural tube Weak 2A
Specimen 2.B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: olfactory placode Present 2B
TS15: otocyst Present 2B
Specimen 2.C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Strong 2C
TS17: trunk dermomyotome Present 2C
TS17: hindbrain Present Regionally restricted 2C Relative expression level between rhombomeres varies.
TS17: neural tube Present 2C Three lateral stripes of expression along the D-V axis of the neural tube are apparent.
Specimen 3.B: embryonic day 8.5 (more )
Note: 8-somite stage.
Structure Level Pattern Image Note
TS13: anterior pro-rhombomere neural fold Present 3B Expression is coincident with Epha4 (Sek-1) expression.
TS13: rhombomere 3 Present 3B Expression is coincident with Epha4 (Sek-1) expression.
TS13: rhombomere 5 Present 3B Expression is coincident with Epha4 (Sek-1) expression.
Specimen not shown: embryonic day 8.0 (more )
Note: 5-somite stage.
Structure Level Pattern Image Note
TS12: anterior pro-rhombomere Present
Specimen 3.C: embryonic day 8.0 (more )
Note: 6-somite stage. Double labeled: blue - Lfng; red - Meox1 (assay MGI:1337797).
Structure Level Pattern Image Note
TS12: trunk unsegmented mesenchyme Present 3C
Specimen 3.D: embryonic day 8.5 (more )
Note: 10-somite stage.
Structure Level Pattern Image Note
TS13: somite 01 Weak 3D
TS13: somite 02 Strong 3D
TS13: head paraxial mesenchyme Present 3D Expression precedes the formation of intersomitic boundaries.
Specimen 3.E: embryonic day 8.5 (more )
Note: 8-somite stage. Double labeled: blue - Lfng; red - Dll1 (assay MGI:1337815).
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Present 3E Expression domain overlaps with Dll1 expression domain at the posterior edge of the anterior Lfng stripe, while more caudally they overlap entirely.
Specimen 4.B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4B Expression is seen in bilateral symmetrical stripes at different dorsal-ventral levels: a ventral stripe that appears to border the floor plate, a narrow medial stripe and a broad domain that includes most of the alar plate.
Specimen 4.E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4E Expression is seen in bilateral symmetrical stripes at different dorsal-ventral levels: a ventral stripe that appears to border the floor plate, a narrow medial stripe and a broad domain that includes most of the alar plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory