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Sumo3 Gene Detail
Summary
  • Symbol
    Sumo3
  • Name
    small ubiquitin-like modifier 3
  • Synonyms
    2810014B19Rik, D10Ertd345e, SMT3A, Smt3h1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336201
    NCBI Gene: 20610
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:77441931-77454165 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336201
protein coding gene Chr10:77441931-77454165 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017400
protein coding gene Chr10:77941999-77983125 (+)
A/J MGP_AJ_G0017377
protein coding gene Chr10:75228140-75264084 (+)
AKR/J MGP_AKRJ_G0017338
protein coding gene Chr10:77236720-77271789 (+)
BALB/cJ MGP_BALBcJ_G0017337
protein coding gene Chr10:75423062-75459619 (+)
C3H/HeJ MGP_C3HHeJ_G0017161
protein coding gene Chr10:77320390-77355974 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017795
protein coding gene Chr10:80657522-80698095 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015485
protein coding gene Chr10:71662706-71698299 (+)
CAST/EiJ MGP_CASTEiJ_G0016731
protein coding gene Chr10:77676850-77715276 (+)
CBA/J MGP_CBAJ_G0017133
protein coding gene Chr10:83780992-83819109 (+)
DBA/2J MGP_DBA2J_G0017238
protein coding gene Chr10:74506322-74541352 (+)
FVB/NJ MGP_FVBNJ_G0017230
protein coding gene Chr10:73679582-73715856 (+)
LP/J MGP_LPJ_G0017311
protein coding gene Chr10:78408177-78443935 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017259
protein coding gene Chr10:85818528-85856301 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017834
protein coding gene Chr10:77313350-77350550 (+)
PWK/PhJ MGP_PWKPhJ_G0016515
protein coding gene Chr10:74386032-74421770 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016298
protein coding gene Chr10:76578583-76612422 (+)
WSB/EiJ MGP_WSBEiJ_G0016794
protein coding gene Chr10:77293329-77329764 (+)



Homology
more
  • Human Ortholog
    SUMO3, small ubiquitin like modifier 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SUMO3, small ubiquitin like modifier 3
  • Synonyms
    SMT3A, Smt3B, SMT3H1, SUMO-3
  • Links
    NCBI Gene ID: 6612
    neXtProt AC: NX_P55854
    UniProt: P55854

  • Chr Location
    21q22.3; chr21:44805617-44818779 (-)  GRCh38

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    41 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    1
  • Targeted
    7
  • Transgenic
    2
  • Genomic Mutations
    5 involving Sumo3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Mice homozygous for a null allele are viable and fertile and exhibit no phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20610 NCBI Gene Model | MGI Sequence Detail 12235 C57BL/6J ±  kb
transcript NM_001301671 RefSeq | MGI Sequence Detail 2756 ZRU/MplStud  
polypeptide Q9Z172 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR022617 Rad60/SUMO-like domain
    IPR000626 Ubiquitin-like domain
    IPR029071 Ubiquitin-like domain superfamily
Molecular
Reagents
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  • All nucleic 217
    Genomic 16
    cDNA 195
    Primer pair 4
    Other 2

    Microarray probesets 4
Other
Accession IDs
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MGI:1196330, MGI:1914744, MGI:2143471, MGI:2143812, MGI:2143846
References
more
  • Summaries
    All 92
    Developmental Gene Expression 15
    Diseases 2
    Gene Ontology 5
    Phenotypes 41
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:343824 Youssef A, et al., Splenic SUMO1 controls systemic inflammation in experimental sepsis. Front Immunol. 2023;14:1200939

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory