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Bop1 Gene Detail
Summary
  • Symbol
    Bop1
  • Name
    block of proliferation 1
  • Synonyms
    Erb1p, mKIAA0124
  • Feature Type
    protein coding gene
  • IDs
    MGI:1334460
    NCBI Gene: 12181
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76337188-76361449 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.91 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    454 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1334460
 protein coding gene Chr15:76337188-76361477 (-)
129S1/SvImJ ENSMUSG00200050762
 protein coding gene Chr15:73451391-73475676 (-)
A/J ENSMUSG00195050477
 protein coding gene Chr15:73425864-73450349 (-)
AKR/J ENSMUSG00220048047
 protein coding gene Chr15:73436865-73461157 (-)
BALB/cJ ENSMUSG00180051561
 protein coding gene Chr15:73251003-73275488 (-)
C3H/HeJ ENSMUSG00175051875
 protein coding gene Chr15:73614430-73638911 (-)
C57BL/6NJ ENSMUSG00215048430
 protein coding gene Chr15:73343227-73367516 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019928
 protein coding gene Chr15:70403589-70427891 (-)
CAST/EiJ ENSTCUG00005044529
 protein coding gene Chr15:72956856-72981351 (-)
CBA/J ENSMUSG00210037295
 protein coding gene Chr15:73389639-73414121 (-)
DBA/2J ENSMUSG00185049066
 protein coding gene Chr15:73366828-73391114 (-)
FVB/NJ ENSMUSG00205044170
 protein coding gene Chr15:73119123-73143607 (-)
JF1/MsJ ENSUMUG00000049817
 protein coding gene Chr15:73019322-73043751 (-)
LP/J ENSMUSG00230052555
 protein coding gene Chr15:76732367-76756849 (-)
NOD/ShiLtJ ENSMUSG00190052012
 protein coding gene Chr15:73372905-73397402 (-)
NZO/HlLtJ ENSMUSG00225050375
 protein coding gene Chr15:77038069-77062563 (-)
PWK/PhJ ENSLUMG00010049351
 protein coding gene Chr15:73311022-73335556 (-)
SPRET/EiJ ENSMSPG00010044245
 protein coding gene Chr15:74916431-74940776 (-)
WSB/EiJ ENSIUOG00005037098
 protein coding gene Chr15:73439064-73463345 (-)



Homology
more
  • Human Ortholog
    BOP1, BOP1 ribosomal biogenesis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BOP1, BOP1 ribosomal biogenesis factor
  • Links
    NCBI Gene ID: 23246
    UniProt: Q14137

  • Chr Location
    8q24.3; chr8:144262045-144291438 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    48
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • Tissues
    53
  • cDNA Data
    118
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12181 NCBI Gene Model | MGI Sequence Detail 24262 C57BL/6J ±  kb
transcript NM_013481 RefSeq | MGI Sequence Detail 2464 ZRU/MplStud  
polypeptide P97452 UniProt | EBI | MGI Sequence Detail 732 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 122
    Genomic 2
    cDNA 120

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146135, MGI:2146201, MGI:2146316
References
more
  • Summaries
    All 76
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 13
    Phenotypes 30
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory