About   Help   FAQ
Bex1 Gene Detail
Summary
  • Symbol
    Bex1
  • Name
    brain expressed X-linked 1
  • Synonyms
    Rex3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328321
    NCBI Gene: 19716
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:135114721-135116262 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 57.40 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328321
 protein coding gene ChrX:135114721-135116262 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036095
 protein coding gene ChrX:133584329-133586329 (-)
A/J MGP_AJ_G0036076
 protein coding gene ChrX:132981494-132982969 (-)
AKR/J MGP_AKRJ_G0036002
 protein coding gene ChrX:137251392-137252867 (-)
BALB/cJ MGP_BALBcJ_G0036064
 protein coding gene ChrX:131367980-131369521 (-)
C3H/HeJ MGP_C3HHeJ_G0035775
 protein coding gene ChrX:133570045-133571034 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036588
 protein coding gene ChrX:137422744-137425887 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033419
 protein coding gene ChrX:124973767-124975242 (-)
CAST/EiJ MGP_CASTEiJ_G0035064
 protein coding gene ChrX:114504694-114662388 (-)
CBA/J MGP_CBAJ_G0035750
 protein coding gene ChrX:141647597-141648586 (-)
DBA/2J MGP_DBA2J_G0035906
 protein coding gene ChrX:132319056-132320597 (-)
FVB/NJ MGP_FVBNJ_G0035841
 protein coding gene ChrX:131499401-131500396 (-)
LP/J MGP_LPJ_G0036001
 protein coding gene ChrX:134507771-134508765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035876
 protein coding gene ChrX:149037452-149038447 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036626
 protein coding gene ChrX:132935834-132936829 (-)
PWK/PhJ MGP_PWKPhJ_G0034756
 protein coding gene ChrX:111403962-111406928 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034586
 protein coding gene ChrX:115136375-115139222 (-)
WSB/EiJ MGP_WSBEiJ_G0035197
 protein coding gene ChrX:131271058-131272635 (-)



Homology
more
  • Human Ortholog
    BEX1, brain expressed X-linked 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BEX1, brain expressed X-linked 1
  • Synonyms
    BEX2, HBEX2, HGR74-h
  • Links
    NCBI Gene ID: 55859
    neXtProt AC: NX_Q9HBH7
    UniProt: Q9HBH7

  • Chr Location
    Xq21-q23; chrX:103062651-103064171 (-)  GRCh38
  • Human Ortholog
    BEX2, brain expressed X-linked 2
  • Synonyms
    BEX1, DJ79P11.1
  • Links
    NCBI Gene ID: 84707
    neXtProt AC: NX_Q9BXY8
    UniProt: Q9BXY8

  • Chr Location
    Xq22.2; chrX:103309346-103311007 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele display impaired exercise performance and abnormal muscle regeneration.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    938
  • Tissues
    79
  • cDNA Data
    56
  • Literature Summary
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19716 NCBI Gene Model | MGI Sequence Detail 1542 C57BL/6J ±  kb
transcript NM_009052 RefSeq | MGI Sequence Detail 890 Not Specified  
polypeptide Q9R224 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007623 Brain-expressed X-linked protein
    IPR021156 Transcription elongation factor A-like/Brain expressed X-linked
Molecular
Reagents
less
  • All nucleic 68
    cDNA 56
    Primer pair 9
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147819, MGI:2147956
References
more
  • Summaries
    All 55
    Developmental Gene Expression 17
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:50125 Faria TN, et al., Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: involvement of cyclin D3 in RA-mediated growth arrest. Mol Cell Endocrinol. 1998 Aug 25;143(1-2):155-66
  • Latest
    J:335283 Alexandre YO, et al., A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity. Sci Immunol. 2022 Jan 7;7(67):eabj0641
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory