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Zc3h7b Gene Detail
Summary
  • Symbol
    Zc3h7b
  • Name
    zinc finger CCCH type containing 7B
  • Synonyms
    Scrg3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328310
    NCBI Gene: 20286
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:81629299-81680470 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1430 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328310
 protein coding gene Chr15:81629258-81680470 (+)
129S1/SvImJ ENSMUSG00200052782
 protein coding gene Chr15:78735971-78787930 (+)
A/J ENSMUSG00195042472
 protein coding gene Chr15:78672408-78724370 (+)
AKR/J ENSMUSG00220051744
 protein coding gene Chr15:78715549-78767509 (+)
BALB/cJ ENSMUSG00180049135
 protein coding gene Chr15:78549360-78601324 (+)
C3H/HeJ ENSMUSG00175042345
 protein coding gene Chr15:78860354-78912311 (+)
C57BL/6NJ ENSMUSG00215052257
 protein coding gene Chr15:78646093-78698053 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020058
 protein coding gene Chr15:75757972-75806555 (+)
CAST/EiJ ENSTCUG00005044441
 protein coding gene Chr15:78163929-78216028 (+)
CBA/J ENSMUSG00210044775
 protein coding gene Chr15:78635448-78687408 (+)
DBA/2J ENSMUSG00185042541
 protein coding gene Chr15:78658660-78710625 (+)
FVB/NJ ENSMUSG00205049929
 protein coding gene Chr15:78376453-78427748 (+)
JF1/MsJ ENSUMUG00000039008
 protein coding gene Chr15:78238318-78290284 (+)
LP/J ENSMUSG00230050713
 protein coding gene Chr15:81983364-82035312 (+)
NOD/ShiLtJ ENSMUSG00190045176
 protein coding gene Chr15:78652540-78704498 (+)
NZO/HlLtJ ENSMUSG00225049295
 protein coding gene Chr15:82319740-82371698 (+)
PWK/PhJ ENSLUMG00010045671
 protein coding gene Chr15:78450355-78501967 (+)
SPRET/EiJ ENSMSPG00010046110
 protein coding gene Chr15:80094116-80143343 (+)
WSB/EiJ ENSIUOG00005040644
 protein coding gene Chr15:78728113-78779747 (+)



Homology
more
  • Human Ortholog
    ZC3H7B, zinc finger CCCH-type containing 7B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZC3H7B, zinc finger CCCH-type containing 7B
  • Synonyms
    RoXaN, ROXAN1
  • Links
    NCBI Gene ID: 23264
    UniProt: Q9UGR2

  • Chr Location
    22q13.2; chr22:41301457-41360155 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    119
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20286 NCBI Gene Model | MGI Sequence Detail 51172 C57BL/6J ±  kb
transcript NM_001081016 RefSeq | MGI Sequence Detail 5699 C57BL/6  
polypeptide NP_001074485 RefSeq | MGI Sequence Detail 982 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR036236 Zinc finger C2H2 superfamily
    IPR039691 Zinc finger CCCH domain-containing protein A/B
    IPR000571 Zinc finger, CCCH-type
    IPR036855 Zinc finger, CCCH-type superfamily
  • GlyGen
    F8VPP8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 122
    Genomic 2
    cDNA 119
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2685473
References
more
  • Summaries
    All 60
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 32
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory