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Ap1g2 Gene Detail
Summary
  • Symbol
    Ap1g2
  • Name
    adaptor protein complex AP-1, gamma 2 subunit
  • Synonyms
    Adtg2, gamma 2-adaptin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328307
    NCBI Gene: 11766
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55336292-55344050 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328307
 protein coding gene Chr14:55336032-55344050 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021340
 protein coding gene Chr14:49099505-49107516 (-)
A/J MGP_AJ_G0021299
 protein coding gene Chr14:48119005-48127020 (-)
AKR/J MGP_AKRJ_G0021275
 protein coding gene Chr14:49868583-49876597 (-)
BALB/cJ MGP_BALBcJ_G0021303
 protein coding gene Chr14:48096623-48104638 (-)
C3H/HeJ MGP_C3HHeJ_G0021083
 protein coding gene Chr14:49558705-49566720 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021741
 protein coding gene Chr14:51588140-51596155 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019288
 protein coding gene Chr14:46524248-46532439 (-)
CAST/EiJ MGP_CASTEiJ_G0020602
 protein coding gene Chr14:45807782-45815796 (-)
CBA/J MGP_CBAJ_G0021050
 protein coding gene Chr14:53143092-53151104 (-)
DBA/2J MGP_DBA2J_G0021171
 protein coding gene Chr14:47858999-47867059 (-)
FVB/NJ MGP_FVBNJ_G0021153
 protein coding gene Chr14:47326515-47334525 (-)
LP/J MGP_LPJ_G0021245
 protein coding gene Chr14:50150032-50158047 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021177
 protein coding gene Chr14:52508406-52516420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021768
 protein coding gene Chr14:49054054-49062065 (-)
PWK/PhJ MGP_PWKPhJ_G0020349
 protein coding gene Chr14:44399194-44407247 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020177
 protein coding gene Chr14:45044901-45052921 (-)
WSB/EiJ MGP_WSBEiJ_G0020655
 protein coding gene Chr14:49349789-49357809 (-)



Homology
more
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 subunit gamma 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 subunit gamma 2
  • Synonyms
    G2AD
  • Links
    NCBI Gene ID: 8906
    neXtProt AC: NX_O75843
    UniProt: O75843

  • Chr Location
    14q11.2; chr14:23559565-23568070 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    8
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 11766 NCBI Gene Model | MGI Sequence Detail 7759 C57BL/6J ±  kb
    transcript NM_007455 RefSeq | MGI Sequence Detail 2688 C57BL/6  
    polypeptide O88512 UniProt | EBI | MGI Sequence Detail 791 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000004092 AP-1 complex subunit gamma-like 2
      (term hierarchy)
    • InterPro Domains
      IPR017107 Adaptor protein complex AP-1, gamma subunit
      IPR011989 Armadillo-like helical
      IPR016024 Armadillo-type fold
      IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
      IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
      IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
      IPR008153 Gamma-adaptin ear (GAE) domain
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:48443 Odorizzi G, et al., The AP-3 complex: a coat of many colours. Trends Cell Biol. 1998 Jul;8(7):282-8
    • Latest
      J:306456 Farini D, et al., A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum. Cell Rep. 2020 Jun 2;31(9):107703
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory