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Grcc10 Gene Detail
Summary
  • Symbol
    Grcc10
  • Name
    gene rich cluster, C10 gene
  • Synonyms
    2310033H05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315201
    NCBI Gene: 14790
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124716146-124718032 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    93 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315201
 protein coding gene Chr6:124716146-124718337 (-)
129S1/SvImJ ENSMUSG00200048278
 protein coding gene Chr6:121777337-121780469 (-)
A/J ENSMUSG00195046738
 protein coding gene Chr6:121235980-121239111 (-)
AKR/J ENSMUSG00220027650
 protein coding gene Chr6:120097555-120100686 (-)
BALB/cJ ENSMUSG00180047867
 protein coding gene Chr6:121574595-121577726 (-)
C3H/HeJ ENSMUSG00175039073
 protein coding gene Chr6:121236056-121239186 (-)
C57BL/6NJ ENSMUSG00215044028
 protein coding gene Chr6:121541084-121544218 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028847
 protein coding gene Chr6:120416842-120419036 (-)
CAST/EiJ ENSTCUG00005046579
 protein coding gene Chr6:121419501-121422359 (-)
CBA/J ENSMUSG00210037799
 protein coding gene Chr6:121275086-121278217 (-)
DBA/2J ENSMUSG00185037766
 protein coding gene Chr6:121974718-121977849 (-)
FVB/NJ ENSMUSG00205040895
 protein coding gene Chr6:120689405-120692540 (-)
JF1/MsJ ENSUMUG00000048326
 protein coding gene Chr6:120383651-120386492 (-)
LP/J ENSMUSG00230040288
 protein coding gene Chr6:123171578-123174709 (-)
NOD/ShiLtJ ENSMUSG00190045158
 protein coding gene Chr6:120946298-120949429 (-)
NZO/HlLtJ ENSMUSG00225015360
 protein coding gene Chr6:125194438-125197571 (-)
PWK/PhJ ENSLUMG00010047656
 protein coding gene Chr6:119650609-119653451 (-)
SPRET/EiJ ENSMSPG00010038365
 protein coding gene Chr6:122502456-122505341 (-)
WSB/EiJ ENSIUOG00005044145
 protein coding gene Chr6:121659694-121662829 (-)



Homology
more
  • Human Ortholog
    C12orf57, chromosome 12 open reading frame 57
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C12orf57, chromosome 12 open reading frame 57
  • Synonyms
    C10, GRCC10
  • Links
    NCBI Gene ID: 113246
    UniProt: Q99622

  • Chr Location
    12p13.31; chr12:6942938-6946003 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human C12orf57 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    656
  • Tissues
    38
  • cDNA Data
    122
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14790 NCBI Gene Model | MGI Sequence Detail 1887 C57BL/6J ±  kb
transcript NM_013535 RefSeq | MGI Sequence Detail 572 ZRU/MplStud  
polypeptide O35127 UniProt | EBI | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 124
    Genomic 1
    cDNA 123

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923999
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory