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Gene Expression Data
Assay Details
Assay
Reference: J:39351 de la Pompa JL, et al., Conservation of the Notch signalling pathway in mammalian neurogenesis. Development. 1997 Mar;124(6):1139-48
Assay type: RNA in situ
MGI Accession ID: MGI:1269967
Gene symbol: Hes5
Gene name: hes family bHLH transcription factor 5
Results
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 4A Expression in a stripe in the midbrain region.
TS13: future hindbrain Present Regionally restricted 4A Expression in two stripes in the hindbrain region.
TS13: neural tube Present 4A Expression in two stripes along the neural tube.
TS13: primitive streak Present 4A Expression in two stripes in the primitive streak.
TS13: trunk unsegmented mesenchyme Present Regionally restricted 4A Expression is in two pairs of stripes in the presomitic mesoderm.
Specimen 4B: embryonic day 8.5; Rbpjtm1Kyo/Rbpjtm1Kyo (more )
Structure Level Pattern Image Note
TS13: future hindbrain Trace 4B Expression is strongly down-regulated in comparison to the wild-type embryo.
TS13: future midbrain Trace 4B Expression is strongly down-regulated in comparison to the wild-type embryo.
TS13: neural tube Trace 4B Expression is strongly down-regulated in comparison to the wild-type embryo.
TS13: primitive streak Trace 4B Expression is strongly down-regulated in comparison to the wild-type embryo.
TS13: trunk unsegmented mesenchyme Trace 4B Expression is strongly down-regulated in comparison to the wild-type embryo.
Specimen 4C: embryonic day 8.5; Notch1tm1Con/Notch1tm1Con (more )
Structure Level Pattern Image Note
TS13: future hindbrain Weak 4C Hes-5 expression was down-regulated in Notch1 mutants, though not as dramatically as in RBP-Jkappa mutants.
TS13: future midbrain Weak 4C Hes-5 expression was down-regulated in Notch1 mutants, though not as dramatically as in RBP-Jkappa mutants.
TS13: neural tube Weak 4C Hes-5 expression was down-regulated in Notch1 mutants, though not as dramatically as in RBP-Jkappa mutants.
TS13: primitive streak Weak 4C Hes-5 expression was down-regulated in Notch1 mutants, though not as dramatically as in RBP-Jkappa mutants.
TS13: trunk unsegmented mesenchyme Weak 4C Hes-5 expression was down-regulated in Notch1 mutants, though not as dramatically as in RBP-Jkappa mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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