About   Help   FAQ
Wipi1 Gene Detail
Summary
  • Symbol
    Wipi1
  • Name
    WD repeat domain, phosphoinositide interacting 1
  • Synonyms
    4930533H01Rik, D11Ertd498e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261864
    NCBI Gene: 52639
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:109464347-109502215 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 72.18 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261864
 protein coding gene Chr11:109464157-109502793 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019336
 protein coding gene Chr11:113140356-113184261 (-)
A/J MGP_AJ_G0019304
 protein coding gene Chr11:108246127-108285046 (-)
AKR/J MGP_AKRJ_G0019273
 protein coding gene Chr11:111496320-111541093 (-)
BALB/cJ MGP_BALBcJ_G0019278
 protein coding gene Chr11:108676782-108716517 (-)
C3H/HeJ MGP_C3HHeJ_G0019087
 protein coding gene Chr11:111797132-111837984 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019728
 protein coding gene Chr11:116566551-116608345 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017351
 protein coding gene Chr11:105469913-105508471 (-)
CAST/EiJ MGP_CASTEiJ_G0018640
 protein coding gene Chr11:112931711-112973243 (-)
CBA/J MGP_CBAJ_G0019056
 protein coding gene Chr11:121383877-121431251 (-)
DBA/2J MGP_DBA2J_G0019168
 protein coding gene Chr11:107721027-107763583 (-)
FVB/NJ MGP_FVBNJ_G0019159
 protein coding gene Chr11:107211795-107250884 (-)
LP/J MGP_LPJ_G0019238
 protein coding gene Chr11:113551080-113596410 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019190
 protein coding gene Chr11:120522467-120565956 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019765
 protein coding gene Chr11:112059043-112101091 (-)
PWK/PhJ MGP_PWKPhJ_G0018405
 protein coding gene Chr11:108890915-108930989 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018197
 protein coding gene Chr11:111838492-111880772 (-)
WSB/EiJ MGP_WSBEiJ_G0018692
 protein coding gene Chr11:111982672-112024909 (-)



Homology
more
  • Human Ortholog
    WIPI1, WD repeat domain, phosphoinositide interacting 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WIPI1, WD repeat domain, phosphoinositide interacting 1
  • Synonyms
    ATG18, ATG18A, WIPI49
  • Links
    NCBI Gene ID: 55062
    neXtProt AC: NX_Q5MNZ9
    UniProt: Q5MNZ9

  • Chr Location
    17q24.2; chr17:68420948-68457513 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    14
  • cDNA Data
    89
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 52639 NCBI Gene Model | MGI Sequence Detail 37869 C57BL/6J ±  kb
    transcript NM_145940 RefSeq | MGI Sequence Detail 1817 ZRU/MplStud  
    polypeptide Q8R3E3 UniProt | EBI | MGI Sequence Detail 446 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 92
      cDNA 91
      Primer pair 1

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:1922049, MGI:2144526
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 5
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:233601 Akinduro O, et al., Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory