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Igdcc3 Gene Detail
Summary
  • Symbol
    Igdcc3
  • Name
    immunoglobulin superfamily, DCC subclass, member 3
  • Synonyms
    2810401C09Rik, Punc, WI-14920
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202390
    NCBI Gene: 19289
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65048471-65093154 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.13 cM, cytoband D-E1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1095 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202390
 protein coding gene Chr9:65048404-65094313 (+)
129S1/SvImJ ENSMUSG00200040677
 protein coding gene Chr9:62152006-62196711 (+)
A/J ENSMUSG00195026232
 protein coding gene Chr9:61867519-61912219 (+)
AKR/J ENSMUSG00220040348
 protein coding gene Chr9:62011471-62056170 (+)
BALB/cJ ENSMUSG00180014770
 protein coding gene Chr9:61999687-62044393 (+)
C3H/HeJ ENSMUSG00175012193
 protein coding gene Chr9:62001227-62045904 (+)
C57BL/6NJ ENSMUSG00215017476
 protein coding gene Chr9:61986746-62031442 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032353
 protein coding gene Chr9:62313902-62360588 (+)
CAST/EiJ ENSTCUG00005030048
 protein coding gene Chr9:61897885-61942839 (+)
CBA/J ENSMUSG00210013745
 protein coding gene Chr9:62082749-62127438 (+)
DBA/2J ENSMUSG00185030002
 protein coding gene Chr9:62106358-62151080 (+)
FVB/NJ ENSMUSG00205020306
 protein coding gene Chr9:62432911-62477886 (+)
JF1/MsJ ENSUMUG00000023249
 protein coding gene Chr9:62161078-62205971 (+)
LP/J ENSMUSG00230024991
 protein coding gene Chr9:62351056-62395756 (+)
NOD/ShiLtJ ENSMUSG00190019130
 protein coding gene Chr9:62195616-62240295 (+)
NZO/HlLtJ ENSMUSG00225044522
 protein coding gene Chr9:62419486-62464200 (+)
PWK/PhJ ENSLUMG00010024464
 protein coding gene Chr9:62130908-62176018 (+)
SPRET/EiJ ENSMSPG00010018283
 protein coding gene Chr9:63184709-63233972 (+)
WSB/EiJ ENSIUOG00005024535
 protein coding gene Chr9:61595909-61640620 (+)



Homology
more
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
  • Synonyms
    HsT18880, PUNC
  • Links
    NCBI Gene ID: 9543
    UniProt: Q8IVU1

  • Chr Location
    15q22.31; chr15:65327127-65378078 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    1 involving Igdcc3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    18 strains or lines available
Homozygotes for a gene trap mutation exhibit reduced performance on the rotarod, suggesting impaired cerebellar function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    922
  • Tissues
    191
  • cDNA Data
    17
  • Literature Summary
    14
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032394 Ensembl Gene Model | MGI Sequence Detail 44684 C57BL/6J ±  kb
transcript ENSMUST00000217371 Ensembl | MGI Sequence Detail 3183 Not Applicable  
polypeptide ENSMUSP00000149084 Ensembl | MGI Sequence Detail 813 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 2
    cDNA 17
    Primer pair 6
    Other 3

    Microarray probesets 6
Other
Accession IDs
less
MGI:1330814, MGI:1917204, MGI:2143154
References
more
  • Summaries
    All 44
    Developmental Gene Expression 14
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:46645 Salbaum JM, Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system. Mech Dev. 1998 Feb;71(1-2):201-4
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory