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Blzf1 Gene Detail
Summary
  • Symbol
    Blzf1
  • Name
    basic leucine zipper nuclear factor 1
  • Synonyms
    1700030G05Rik, Blzf1l, Golgin-45, Jem-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201607
    NCBI Gene: 66352
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:164117368-164135056 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 71.60 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    521 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201607
 protein coding gene Chr1:164117368-164135058 (-)
129S1/SvImJ ENSMUSG00200005685
 protein coding gene Chr1:161588187-161605878 (-)
A/J ENSMUSG00195020801
 protein coding gene Chr1:160928423-160946115 (-)
AKR/J ENSMUSG00220012891
 protein coding gene Chr1:160709086-160726775 (-)
BALB/cJ ENSMUSG00180034186
 protein coding gene Chr1:161170369-161188059 (-)
C3H/HeJ ENSMUSG00175035839
 protein coding gene Chr1:161260989-161278680 (-)
C57BL/6NJ ENSMUSG00215038124
 protein coding gene Chr1:161138199-161155888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014795
 protein coding gene Chr1:154776050-154792891 (-)
CAST/EiJ ENSTCUG00005020123
 protein coding gene Chr1:159734631-159752343 (-)
CBA/J ENSMUSG00210021177
 protein coding gene Chr1:161133606-161151295 (-)
DBA/2J ENSMUSG00185010415
 protein coding gene Chr1:165365867-165383570 (-)
FVB/NJ ENSMUSG00205007696
 protein coding gene Chr1:160209494-160227198 (-)
JF1/MsJ ENSUMUG00000007126
 protein coding gene Chr1:164516213-164533903 (-)
LP/J ENSMUSG00230021480
 protein coding gene Chr1:164998612-165016301 (-)
NOD/ShiLtJ ENSMUSG00190024567
 protein coding gene Chr1:160974471-160992175 (-)
NZO/HlLtJ ENSMUSG00225003302
 protein coding gene Chr1:168592009-168609698 (-)
PWK/PhJ ENSLUMG00010042543
 protein coding gene Chr1:159902705-159920365 (-)
SPRET/EiJ ENSMSPG00010037467
 protein coding gene Chr1:163411153-163426893 (-)
WSB/EiJ ENSIUOG00005014094
 protein coding gene Chr1:160472817-160490504 (-)



Homology
more
  • Human Ortholog
    BLZF1, basic leucine zipper nuclear factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BLZF1, basic leucine zipper nuclear factor 1
  • Synonyms
    GOLGIN-45, JEM-1, JEM1, JEM-1s
  • Links
    NCBI Gene ID: 8548
    UniProt: Q9H2G9

  • Chr Location
    1q24.2; chr1:169367970-169396575 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    73
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66352 NCBI Gene Model | MGI Sequence Detail 17689 C57BL/6J ±  kb
transcript NM_001357052 RefSeq | MGI Sequence Detail 4095 C57BL/6  
polypeptide Q8R2X8 UniProt | EBI | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 74
    cDNA 74

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913602
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:39644 Duprez E, et al., JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia. Oncogene. 1997 Apr 3;14(13):1563-70
  • Latest
    J:366840 Brito S, et al., Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control. Dev Cell. 2025 May 5;60(9):1304-1320.e7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory