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Kcns2 Gene Detail
Summary
  • Symbol
    Kcns2
  • Name
    K+ voltage-gated channel, subfamily S, 2
  • Synonyms
    E130006J24Rik, Kv9.2
Location &
Maps
more
  • Sequence Map
    Chr15:34837501-34843553 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 14.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    173 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1197011
 protein coding gene Chr15:34837501-34843553 (+)
129S1/SvImJ ENSMUSG00200024803
 protein coding gene Chr15:31841450-31847504 (+)
A/J ENSMUSG00195034781
 protein coding gene Chr15:31768451-31774503 (+)
AKR/J ENSMUSG00220028745
 protein coding gene Chr15:31671917-31677969 (+)
BALB/cJ ENSMUSG00180030106
 protein coding gene Chr15:31725746-31731798 (+)
C3H/HeJ ENSMUSG00175025849
 protein coding gene Chr15:31904262-31910314 (+)
C57BL/6NJ ENSMUSG00215012184
 protein coding gene Chr15:31746810-31752861 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019728
 protein coding gene Chr15:29782886-29787861 (+)
CAST/EiJ ENSTCUG00005009973
 protein coding gene Chr15:31779104-31785155 (+)
CBA/J ENSMUSG00210017773
 protein coding gene Chr15:31852035-31858087 (+)
DBA/2J ENSMUSG00185033494
 protein coding gene Chr15:31836828-31842880 (+)
FVB/NJ ENSMUSG00205028111
 protein coding gene Chr15:31729770-31735822 (+)
JF1/MsJ ENSUMUG00000019038
 protein coding gene Chr15:31752407-31758459 (+)
LP/J ENSMUSG00230012320
 protein coding gene Chr15:35237859-35243913 (+)
NOD/ShiLtJ ENSMUSG00190027387
 protein coding gene Chr15:31805159-31811213 (+)
NZO/HlLtJ ENSMUSG00225031444
 protein coding gene Chr15:35528285-35534337 (+)
PWK/PhJ ENSLUMG00010028922
 protein coding gene Chr15:31899997-31906050 (+)
SPRET/EiJ ENSMSPG00010012863
 protein coding gene Chr15:32515268-32521321 (+)
WSB/EiJ ENSIUOG00005030418
 protein coding gene Chr15:31846449-31852504 (+)



Homology
more
  • Human Ortholog
    KCNS2, potassium voltage-gated channel modifier subfamily S member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNS2, potassium voltage-gated channel modifier subfamily S member 2
  • Synonyms
    KV9.2
  • Links
    NCBI Gene ID: 3788
    UniProt: Q9ULS6

  • Chr Location
    8q22.2; chr8:98426958-98432853 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in no obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    4
  • cDNA Data
    9
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 16539 NCBI Gene Model | MGI Sequence Detail 6053 C57BL/6J ±  kb
    transcript NM_181317 RefSeq | MGI Sequence Detail 5473 Not Specified  
    polypeptide O35174 UniProt | EBI | MGI Sequence Detail 477 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2443152
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory