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Tmem141 Gene Detail
Summary
  • Symbol
    Tmem141
  • Name
    transmembrane protein 141
  • Synonyms
    1110065P14Rik, D2Ertd217e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098773
    NCBI Gene: 51875
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25510079-25512017 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.57 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098773
 protein coding gene Chr2:25510078-25512059 (-)
129S1/SvImJ ENSMUSG00200049215
 protein coding gene Chr2:22494233-22496171 (-)
A/J ENSMUSG00195043546
 protein coding gene Chr2:22584297-22586235 (-)
AKR/J ENSMUSG00220048805
 protein coding gene Chr2:22702125-22704063 (-)
BALB/cJ ENSMUSG00180054247
 protein coding gene Chr2:22595893-22597831 (-)
C3H/HeJ ENSMUSG00175047713
 protein coding gene Chr2:22560040-22561978 (-)
C57BL/6NJ ENSMUSG00215042301
 protein coding gene Chr2:22618781-22620719 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023288
 protein coding gene Chr2:21518771-21520874 (-)
CAST/EiJ ENSTCUG00005050707
 protein coding gene Chr2:22345045-22346990 (-)
CBA/J ENSMUSG00210016702
 protein coding gene Chr2:22599018-22600956 (-)
DBA/2J ENSMUSG00185051323
 protein coding gene Chr2:22498480-22500418 (-)
FVB/NJ ENSMUSG00205047688
 protein coding gene Chr2:22352855-22354793 (-)
JF1/MsJ ENSUMUG00000026190
 protein coding gene Chr2:22418820-22420761 (-)
LP/J ENSMUSG00230041689
 protein coding gene Chr2:24430220-24432158 (-)
NOD/ShiLtJ ENSMUSG00190050021
 protein coding gene Chr2:22589344-22591282 (-)
NZO/HlLtJ ENSMUSG00225008989
 protein coding gene Chr2:32180655-32182593 (-)
PWK/PhJ ENSLUMG00010044446
 protein coding gene Chr2:22515666-22517611 (-)
SPRET/EiJ ENSMSPG00010034761
 protein coding gene Chr2:23196618-23198765 (-)
WSB/EiJ ENSIUOG00005051366
 protein coding gene Chr2:22456380-22458318 (-)



Homology
more
  • Human Ortholog
    TMEM141, transmembrane protein 141
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM141, transmembrane protein 141
  • Links
    NCBI Gene ID: 85014
    UniProt: Q96I45

  • Chr Location
    9q34.3; chr9:136791303-136793317 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    20
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026939 Ensembl Gene Model | MGI Sequence Detail 1939 C57BL/6J ±  kb
transcript ENSMUST00000142087 Ensembl | MGI Sequence Detail 795 Not Applicable  
polypeptide ENSMUSP00000121862 Ensembl | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 20
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916159, MGI:2139042
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory