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Coa3 Gene Detail
Summary
  • Symbol
    Coa3
  • Name
    cytochrome C oxidase assembly factor 3
  • Synonyms
    1810033A19Rik, Ccdc56, D11Ertd99e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098757
    NCBI Gene: 52469
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101168796-101169774 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 64.56 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098757
 protein coding gene Chr11:101168794-101169940 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019191
 protein coding gene Chr11:104121127-104122273 (-)
A/J MGP_AJ_G0019159
 protein coding gene Chr11:99744957-99746106 (-)
AKR/J MGP_AKRJ_G0019128
 protein coding gene Chr11:102845742-102846888 (-)
BALB/cJ MGP_BALBcJ_G0019133
 protein coding gene Chr11:100231907-100233053 (-)
C3H/HeJ MGP_C3HHeJ_G0018942
 protein coding gene Chr11:103020021-103021167 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019582
 protein coding gene Chr11:107371648-107372794 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017208
 protein coding gene Chr11:97158310-97159471 (-)
CAST/EiJ MGP_CASTEiJ_G0018496
 protein coding gene Chr11:104008437-104009584 (-)
CBA/J MGP_CBAJ_G0018911
 protein coding gene Chr11:111811164-111812310 (-)
DBA/2J MGP_DBA2J_G0019023
 protein coding gene Chr11:99274081-99275227 (-)
FVB/NJ MGP_FVBNJ_G0019013
 protein coding gene Chr11:98820313-98821459 (-)
LP/J MGP_LPJ_G0019092
 protein coding gene Chr11:104666136-104667282 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019044
 protein coding gene Chr11:111366654-111367800 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019620
 protein coding gene Chr11:103172840-103173986 (-)
PWK/PhJ MGP_PWKPhJ_G0018259
 protein coding gene Chr11:100328519-100329665 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018051
 protein coding gene Chr11:102910821-102911964 (-)
WSB/EiJ MGP_WSBEiJ_G0018545
 protein coding gene Chr11:103169113-103170259 (-)



Homology
more
  • Human Ortholog
    COA3, cytochrome c oxidase assembly factor 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COA3, cytochrome c oxidase assembly factor 3
  • Synonyms
    CCDC56, COX25, hCOA3, HSPC009, MC4DN14, MITRAC12
  • Links
    NCBI Gene ID: 28958
    neXtProt AC: NX_Q9Y2R0
    UniProt: Q9Y2R0

  • Chr Location
    17q21.2; chr17:42795147-42798704 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COA3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    102
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52469 NCBI Gene Model | MGI Sequence Detail 979 C57BL/6J ±  kb
transcript NM_026618 RefSeq | MGI Sequence Detail 718 ZRU/MplStud  
polypeptide Q9D2R6 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029331 coiled-coil domain-containing protein 56
    (term hierarchy)
  • InterPro Domains
    IPR041752 Cytochrome c oxidase assembly factor 3, mitochondrial
    IPR018628 Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain
Molecular
Reagents
less
  • All nucleic 103
    cDNA 102
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915463
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:266583 Baumgartner M, et al., Minor spliceosome inactivation causes microcephaly, owing to cell cycle defects and death of self-amplifying radial glial cells. Development. 2018 Aug 28;145(17):dev166322
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory