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Alg3 Gene Detail
Summary
  • Symbol
    Alg3
  • Name
    ALG3 alpha-1,3- mannosyltransferase
  • Synonyms
    D16Ertd36e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098592
    NCBI Gene: 208624
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:20424208-20429515 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 12.48 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098592
 protein coding gene Chr16:20424124-20430485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022647
 protein coding gene Chr16:17942874-17948191 (-)
A/J MGP_AJ_G0022609
 protein coding gene Chr16:17079932-17085246 (-)
AKR/J MGP_AKRJ_G0022584
 protein coding gene Chr16:17726588-17731905 (-)
BALB/cJ MGP_BALBcJ_G0022613
 protein coding gene Chr16:17237599-17242916 (-)
C3H/HeJ MGP_C3HHeJ_G0022378
 protein coding gene Chr16:17892828-17898145 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023064
 protein coding gene Chr16:18290183-18295500 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020581
 protein coding gene Chr16:17765534-17770857 (-)
CAST/EiJ MGP_CASTEiJ_G0021908
 protein coding gene Chr16:17866942-17872251 (-)
CBA/J MGP_CBAJ_G0022350
 protein coding gene Chr16:19043183-19048500 (-)
DBA/2J MGP_DBA2J_G0022482
 protein coding gene Chr16:17006222-17011539 (-)
FVB/NJ MGP_FVBNJ_G0022457
 protein coding gene Chr16:17041723-17047040 (-)
LP/J MGP_LPJ_G0022549
 protein coding gene Chr16:17674696-17680013 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022477
 protein coding gene Chr16:18723403-18728720 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023075
 protein coding gene Chr16:17691864-17697181 (-)
PWK/PhJ MGP_PWKPhJ_G0021649
 protein coding gene Chr16:17268775-17274569 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021478
 protein coding gene Chr16:17489450-17495533 (-)
WSB/EiJ MGP_WSBEiJ_G0021952
 protein coding gene Chr16:17682585-17691121 (-)



Homology
more
  • Human Ortholog
    ALG3, ALG3 alpha-1,3- mannosyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALG3, ALG3 alpha-1,3- mannosyltransferase
  • Synonyms
    CDG1D, CDGS4, CDGS6, D16Ertd36e, not, Not56, NOT56L
  • Links
    NCBI Gene ID: 10195
    neXtProt AC: NX_Q92685
    UniProt: Q92685

  • Chr Location
    3q27.1; chr3:184242301-184249548 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ALG3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    814
  • Tissues
    103
  • cDNA Data
    42
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 208624 NCBI Gene Model | MGI Sequence Detail 5308 C57BL/6J ±  kb
transcript NM_145939 RefSeq | MGI Sequence Detail 1437 ZRU/MplStud  
polypeptide Q8K2A8 UniProt | EBI | MGI Sequence Detail 438 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:50320 Pappano WN, et al., Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes. Genomics. 1998 Sep 1;52(2):236-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory