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Tead3 Gene Detail
Summary
  • Symbol
    Tead3
  • Name
    TEA domain family member 3
  • Synonyms
    DTEF-1, ETFR-1, Tcf13r2, TEAD-3, TEF-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:109241
    NCBI Gene: 21678
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28550645-28569779 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 14.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109241
 protein coding gene Chr17:28550645-28569791 (-)
129S1/SvImJ ENSMUSG00200051271
 protein coding gene Chr17:24208915-24228068 (-)
A/J ENSMUSG00195049378
 protein coding gene Chr17:25025367-25044514 (-)
AKR/J ENSMUSG00220044622
 protein coding gene Chr17:24072995-24092139 (-)
BALB/cJ ENSMUSG00180032161
 protein coding gene Chr17:24511386-24530546 (-)
C3H/HeJ ENSMUSG00175046418
 protein coding gene Chr17:24061449-24080590 (-)
C57BL/6NJ ENSMUSG00215052526
 protein coding gene Chr17:24061367-24080515 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021319
 protein coding gene Chr17:24185490-24204236 (-)
CAST/EiJ ENSTCUG00005043522
 protein coding gene Chr17:24804666-24823807 (-)
CBA/J ENSMUSG00210047743
 protein coding gene Chr17:23899895-23919037 (-)
DBA/2J ENSMUSG00185051593
 protein coding gene Chr17:26114807-26133959 (-)
FVB/NJ ENSMUSG00205047989
 protein coding gene Chr17:24376375-24395522 (-)
JF1/MsJ ENSUMUG00000053518
 protein coding gene Chr17:25576932-25596064 (-)
LP/J ENSMUSG00230055028
 protein coding gene Chr17:27634761-27653913 (-)
NOD/ShiLtJ ENSMUSG00190035815
 protein coding gene Chr17:24008822-24027977 (-)
NZO/HlLtJ ENSMUSG00225051049
 protein coding gene Chr17:29602697-29621848 (-)
PWK/PhJ ENSLUMG00010051878
 protein coding gene Chr17:23501216-23520372 (-)
SPRET/EiJ ENSMSPG00010039300
 protein coding gene Chr17:24791923-24811211 (-)
WSB/EiJ ENSIUOG00005049231
 protein coding gene Chr17:24768848-24787962 (-)



Homology
more
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
  • Synonyms
    DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF-5, TEF5
  • Links
    NCBI Gene ID: 7005
    UniProt: Q99594

  • Chr Location
    6p21.31; chr6:35473597-35497079 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    910
  • Tissues
    182
  • cDNA Data
    66
  • Literature Summary
    22
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21678 NCBI Gene Model | MGI Sequence Detail 19135 C57BL/6J ±  kb
    transcript NM_001204156 RefSeq | MGI Sequence Detail 2775 ZRU/MplStud  
    polypeptide P70210 UniProt | EBI | MGI Sequence Detail 439 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 77
      Genomic 2
      cDNA 67
      Primer pair 5
      Other 3

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-38286, MGI:2147049
    References
    more
    • Summaries
      All 74
      Developmental Gene Expression 22
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
    • Latest
      J:369755 Perry CH, et al., TEAD switches interacting partners along neural progenitor lineage progression to execute distinct functions. Genes Dev. 2025 Jul 1;39(13-14):849-867
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory