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Elavl3 Gene Detail
Summary
  • Symbol
    Elavl3
  • Name
    ELAV like RNA binding protein 3
  • Synonyms
    2600009P04Rik, Huc, mHuC
  • Feature Type
    protein coding gene
  • IDs
    MGI:109157
    NCBI Gene: 15571
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21926301-21963319 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 8.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    785 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109157
 protein coding gene Chr9:21926301-21963442 (-)
129S1/SvImJ ENSMUSG00200044412
 protein coding gene Chr9:18880607-18917880 (-)
A/J ENSMUSG00195033111
 protein coding gene Chr9:18717245-18754525 (-)
AKR/J ENSMUSG00220025949
 protein coding gene Chr9:18719661-18756949 (-)
BALB/cJ ENSMUSG00180038245
 protein coding gene Chr9:18851532-18888815 (-)
C3H/HeJ ENSMUSG00175039485
 protein coding gene Chr9:18814057-18851341 (-)
C57BL/6NJ ENSMUSG00215016959
 protein coding gene Chr9:18811355-18848633 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031894
 protein coding gene Chr9:18019695-18057100 (-)
CAST/EiJ ENSTCUG00005026347
 protein coding gene Chr9:18857758-18894487 (-)
CBA/J ENSMUSG00210038168
 protein coding gene Chr9:18795013-18832277 (-)
DBA/2J ENSMUSG00185025776
 protein coding gene Chr9:18910301-18947574 (-)
FVB/NJ ENSMUSG00205037387
 protein coding gene Chr9:19146267-19183518 (-)
JF1/MsJ ENSUMUG00000015910
 protein coding gene Chr9:19011682-19049055 (-)
LP/J ENSMUSG00230038426
 protein coding gene Chr9:19305485-19342720 (-)
NOD/ShiLtJ ENSMUSG00190022937
 protein coding gene Chr9:18839253-18876501 (-)
NZO/HlLtJ ENSMUSG00225048505
 protein coding gene Chr9:19252263-19289525 (-)
PWK/PhJ ENSLUMG00010039301
 protein coding gene Chr9:18902995-18940271 (-)
SPRET/EiJ ENSMSPG00010019373
 protein coding gene Chr9:19127638-19163947 (-)
WSB/EiJ ENSIUOG00005039696
 protein coding gene Chr9:18381216-18418576 (-)



Homology
more
  • Human Ortholog
    ELAVL3, ELAV like RNA binding protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELAVL3, ELAV like RNA binding protein 3
  • Synonyms
    HUC, HUCL, PLE21
  • Links
    NCBI Gene ID: 1995
    UniProt: Q14576

  • Chr Location
    19p13.2; chr19:11451326-11481051 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit strain-specific preweaning lethality, abnormal cortical hypersynchronization and non-convulsive electropgraphic seizure. Mice heterozygous for the allele exhibit abnormal brain wave pattern and spike wave discharge.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    94
  • cDNA Data
    15
  • Literature Summary
    151
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003410 Ensembl Gene Model | MGI Sequence Detail 37019 C57BL/6J ±  kb
transcript ENSMUST00000003501 Ensembl | MGI Sequence Detail 5014 Not Applicable  
polypeptide ENSMUSP00000003501 Ensembl | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 1
    cDNA 17
    Primer pair 1
    Antibodies 14

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-38201, MGI:1913822
References
more
  • Summaries
    All 198
    Developmental Gene Expression 151
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:25297 Wolff GL, et al., Diabetogenic response to streptozotocin varies among obese yellow and among lean agouti (BALB/c x VY)F1 hybrid mice. Proc Soc Exp Biol Med. 1990 Feb;193(2):155-63
  • Latest
    J:388926 Hsu IY, et al., Lineage and organ signals sequentially build organ intrinsic nervous systems. Nature. 2026 May 13;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory