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Camp Gene Detail
Summary
  • Symbol
    Camp
  • Name
    cathelicidin antimicrobial peptide
  • Synonyms
    CAP18, Cnlp, Cramp, FALL39, MCLP
  • Feature Type
    protein coding gene
  • IDs
    MGI:108443
    NCBI Gene: 12796
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:109676445-109678524 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    41 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108443
 protein coding gene Chr9:109676445-109678685 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035338
 protein coding gene Chr9:111941448-111943653 (-)
A/J MGP_AJ_G0035319
 protein coding gene Chr9:107896185-107898890 (-)
AKR/J MGP_AKRJ_G0035250
 protein coding gene Chr9:110567681-110569908 (-)
BALB/cJ MGP_BALBcJ_G0035314
 protein coding gene Chr9:107633685-107637005 (-)
C3H/HeJ MGP_C3HHeJ_G0035022
 protein coding gene Chr9:111032736-111034943 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035836
 protein coding gene Chr9:114987204-114991069 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032722
 protein coding gene Chr9:105131352-105133408 (-)
CAST/EiJ MGP_CASTEiJ_G0034328
 protein coding gene Chr9:110847413-110851511 (-)
CBA/J MGP_CBAJ_G0034989
 protein coding gene Chr9:119255295-119257324 (-)
DBA/2J MGP_DBA2J_G0035148
 protein coding gene Chr9:107357178-107359420 (-)
FVB/NJ MGP_FVBNJ_G0035095
 protein coding gene Chr9:106184301-106187119 (-)
LP/J MGP_LPJ_G0035227
 protein coding gene Chr9:112254540-112256754 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035135
 protein coding gene Chr9:120629420-120633124 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035856
 protein coding gene Chr9:110866576-110871445 (-)
PWK/PhJ MGP_PWKPhJ_G0034035
 protein coding gene Chr9:107577373-107579583 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033870
 protein coding gene Chr9:110952204-110956805 (-)
WSB/EiJ MGP_WSBEiJ_G0034449
 protein coding gene Chr9:110761418-110764974 (-)



Homology
more
  • Human Ortholog
    CAMP, cathelicidin antimicrobial peptide
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAMP, cathelicidin antimicrobial peptide
  • Synonyms
    CAP18, CAP-18, CRAMP, FALL39, FALL-39, HSD26, LL37
  • Links
    NCBI Gene ID: 820
    neXtProt AC: NX_P49913
    UniProt: P49913

  • Chr Location
    3p21.31; chr3:48223347-48225491 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 3 genetic backgrounds
    62 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli and F. solani-induced keratitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    47
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    19
  • cDNA Data
    16
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12796 NCBI Gene Model | MGI Sequence Detail 2080 C57BL/6J ±  kb
    transcript NM_009921 RefSeq | MGI Sequence Detail 599 ZRU/MplStud  
    polypeptide P51437 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 17
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-37487, MGI:892985
    References
    more
    • Summaries
      All 106
      Developmental Gene Expression 3
      Gene Ontology 11
      Phenotypes 62
    • Earliest
      J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
    • Latest
      J:328783 Smith KJ, et al., The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation. PLoS Biol. 2022 Aug;20(8):e3001554
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory