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Uqcrq Gene Detail
Summary
  • Symbol
    Uqcrq
  • Name
    ubiquinol-cytochrome c reductase, complex III subunit VII
  • Synonyms
    1100001F06Rik, 1500040F11Rik, 5830407L17Rik, c1502, Qpc, QP-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:107807
    NCBI Gene: 22272
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:53318749-53321658 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 31.94 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107807
 protein coding gene Chr11:53318749-53321658 (-)
129S1/SvImJ ENSMUSG00200038091
 protein coding gene Chr11:50314584-50317489 (-)
A/J ENSMUSG00195031625
 protein coding gene Chr11:50251840-50254745 (-)
AKR/J ENSMUSG00220030201
 protein coding gene Chr11:50440709-50443615 (-)
BALB/cJ ENSMUSG00180035178
 protein coding gene Chr11:50313275-50316180 (-)
C3H/HeJ ENSMUSG00175035300
 protein coding gene Chr11:50283127-50286032 (-)
C57BL/6NJ ENSMUSG00215021408
 protein coding gene Chr11:50105924-50108829 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016333
 protein coding gene Chr11:48368277-48371179 (-)
CAST/EiJ ENSTCUG00005042980
 protein coding gene Chr11:49876594-49879491 (-)
CBA/J ENSMUSG00210026978
 protein coding gene Chr11:50139093-50141998 (-)
DBA/2J ENSMUSG00185024328
 protein coding gene Chr11:50351101-50354005 (-)
FVB/NJ ENSMUSG00205019347
 protein coding gene Chr11:50181422-50184327 (-)
JF1/MsJ ENSUMUG00000043129
 protein coding gene Chr11:50726442-50729344 (-)
LP/J ENSMUSG00230049537
 protein coding gene Chr11:51532265-51535170 (-)
NOD/ShiLtJ ENSMUSG00190030688
 protein coding gene Chr11:50416288-50419322 (-)
NZO/HlLtJ ENSMUSG00225032598
 protein coding gene Chr11:53573207-53576111 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UQCRQ, ubiquinol-cytochrome c reductase complex III subunit VII
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UQCRQ, ubiquinol-cytochrome c reductase complex III subunit VII
  • Synonyms
    MC3DN4, QCR8, QP-C, QPC, UQCR7
  • Links
    NCBI Gene ID: 27089
    UniProt: O14949

  • Chr Location
    5q31.1; chr5:132866626-132868847 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UQCRQ associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    34
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    26
  • Targeted
    5
  • Genomic Mutations
    1 involving Uqcrq
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    134
  • cDNA Data
    264
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22272 NCBI Gene Model | MGI Sequence Detail 2910 C57BL/6J ±  kb
transcript NM_025352 RefSeq | MGI Sequence Detail 1525 Not Specified  
polypeptide Q9CQ69 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 271
    cDNA 266
    Primer pair 3
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36384, MGI:1913349, MGI:1915190, MGI:1923247, MGI:2138135
References
more
  • Summaries
    All 77
    Developmental Gene Expression 8
    Gene Ontology 15
    Phenotypes 30
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:382533 Karakousi T, et al., IFNgamma-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma. Cancer Cell. 2026 Jan 22;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory