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Myo7b Gene Detail
Summary
  • Symbol
    Myo7b
  • Name
    myosin VIIB
  • Feature Type
    protein coding gene
  • IDs
    MGI:107709
    NCBI Gene: 17922
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:32092287-32169984 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 17.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2319 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107709
 protein coding gene Chr18:32092287-32170014 (-)
129S1/SvImJ ENSMUSG00200016026
 protein coding gene Chr18:29090596-29167600 (-)
A/J ENSMUSG00195002367
 protein coding gene Chr18:29281649-29358891 (-)
AKR/J ENSMUSG00220011258
 protein coding gene Chr18:29239416-29317158 (-)
BALB/cJ ENSMUSG00180003484
 protein coding gene Chr18:29746867-29824610 (-)
C3H/HeJ ENSMUSG00175023399
 protein coding gene Chr18:29262159-29339922 (-)
C57BL/6NJ ENSMUSG00215017991
 protein coding gene Chr18:28962810-29040552 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022071
 protein coding gene Chr18:29314757-29392590 (-)
CAST/EiJ ENSTCUG00005015552
 protein coding gene Chr18:28897729-28976402 (-)
CBA/J ENSMUSG00210015760
 protein coding gene Chr18:29280577-29357816 (-)
DBA/2J ENSMUSG00185022470
 protein coding gene Chr18:29215176-29292412 (-)
FVB/NJ ENSMUSG00205017520
 protein coding gene Chr18:28948938-29026680 (-)
JF1/MsJ ENSUMUG00000015849
 protein coding gene Chr18:29340288-29416790 (-)
LP/J ENSMUSG00230043801
 protein coding gene Chr18:31288214-31365203 (-)
NOD/ShiLtJ ENSMUSG00190006628
 protein coding gene Chr18:29009183-29086420 (-)
NZO/HlLtJ ENSMUSG00225045116
 protein coding gene Chr18:31212723-31289948 (-)
PWK/PhJ ENSLUMG00010003041
 protein coding gene Chr18:29488032-29565739 (-)
SPRET/EiJ ENSMSPG00010021440
 protein coding gene Chr18:29513237-29592645 (-)
WSB/EiJ ENSIUOG00005002691
 protein coding gene Chr18:29020592-29097829 (-)



Homology
more
  • Human Ortholog
    MYO7B, myosin VIIB
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYO7B, myosin VIIB
  • Links
    NCBI Gene ID: 4648
    UniProt: Q6PIF6

  • Chr Location
    2q14.3; chr2:127535683-127637729 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    617
  • Tissues
    8
  • cDNA Data
    13
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17922 NCBI Gene Model | MGI Sequence Detail 77698 C57BL/6J ±  kb
    transcript NM_032394 RefSeq | MGI Sequence Detail 6591 Not Specified  
    polypeptide Q99MZ6 UniProt | EBI | MGI Sequence Detail 2113 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-36285
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory