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Atp5mc1 Gene Detail
Summary
  • Symbol
    Atp5mc1
  • Name
    ATP synthase membrane subunit c locus 1
  • Synonyms
    Atp5g1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107653
    NCBI Gene: 11951
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:95963619-95966520 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.33 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107653
 protein coding gene Chr11:95959678-95966520 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018997
 protein coding gene Chr11:98346844-98354870 (-)
A/J MGP_AJ_G0018965
 protein coding gene Chr11:94348267-94354510 (-)
AKR/J MGP_AKRJ_G0018935
 protein coding gene Chr11:97255684-97262688 (-)
BALB/cJ MGP_BALBcJ_G0018938
 protein coding gene Chr11:94832779-94839595 (-)
C3H/HeJ MGP_C3HHeJ_G0018752
 protein coding gene Chr11:97397139-97404025 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019390
 protein coding gene Chr11:101423868-101430730 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017020
 protein coding gene Chr11:91836299-91843901 (-)
CAST/EiJ MGP_CASTEiJ_G0018306
 protein coding gene Chr11:98209940-98218898 (-)
CBA/J MGP_CBAJ_G0018723
 protein coding gene Chr11:105571620-105581567 (-)
DBA/2J MGP_DBA2J_G0018831
 protein coding gene Chr11:93918540-93925359 (-)
FVB/NJ MGP_FVBNJ_G0018820
 protein coding gene Chr11:93393823-93400638 (-)
LP/J MGP_LPJ_G0018901
 protein coding gene Chr11:98898051-98904869 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018847
 protein coding gene Chr11:105572232-105579271 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019430
 protein coding gene Chr11:97554700-97564389 (-)
PWK/PhJ MGP_PWKPhJ_G0018077
 protein coding gene Chr11:94862935-94877117 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017866
 protein coding gene Chr11:97263657-97272352 (-)
WSB/EiJ MGP_WSBEiJ_G0018355
 protein coding gene Chr11:97453748-97460490 (-)



Homology
more
  • Human Ortholog
    ATP5MC1, ATP synthase membrane subunit c locus 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5MC1, ATP synthase membrane subunit c locus 1
  • Synonyms
    ATP5A, ATP5G, ATP5G1
  • Links
    NCBI Gene ID: 516
    neXtProt AC: NX_P05496
    UniProt: P05496

  • Chr Location
    17q21.32; chr17:48892765-48895871 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    15
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    847
  • Tissues
    128
  • cDNA Data
    140
  • Literature Summary
    10
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 11951 NCBI Gene Model | MGI Sequence Detail 2902 C57BL/6J ±  kb
transcript NM_001161419 RefSeq | MGI Sequence Detail 805 C57BL/6  
polypeptide Q9CR84 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030667 ATP synthase F(0) complex subunit C1, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR000454 ATP synthase, F0 complex, subunit C
    IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site
    IPR038662 F1F0 ATP synthase subunit C superfamily
    IPR035921 F/V-ATP synthase subunit C superfamily
    IPR002379 V-ATPase proteolipid subunit C-like domain
Molecular
Reagents
less
  • All nucleic 142
    cDNA 140
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36227
References
more
  • Summaries
    All 60
    Developmental Gene Expression 10
    Gene Ontology 9
    Phenotypes 15
  • Earliest
    J:50113 Taylor KD, et al., Patterns of mRNA prevalence and expression of B1 and B2 transcripts in early mouse embryos. Development. 1987 Dec;101(4):877-92
  • Latest
    J:321746 Yu H, et al., LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. 2021;143(20):2007-2022
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory