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Rgs7bp Gene Detail
Summary
  • Symbol
    Rgs7bp
  • Name
    regulator of G-protein signalling 7 binding protein
  • Synonyms
    A930030I01Rik, D13Bwg1146e, R7bp
  • Feature Type
    protein coding gene
  • IDs
    MGI:106334
    NCBI Gene: 52882
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:105082412-105191438 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 56.90 cM, cytoband D1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    530 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106334
 protein coding gene Chr13:105082412-105191438 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020912
 protein coding gene Chr13:107077352-107187665 (-)
A/J MGP_AJ_G0020863
 protein coding gene Chr13:102903571-103011955 (-)
AKR/J MGP_AKRJ_G0020838
 protein coding gene Chr13:106030020-106146212 (-)
BALB/cJ MGP_BALBcJ_G0020863
 protein coding gene Chr13:103612409-103718904 (-)
C3H/HeJ MGP_C3HHeJ_G0020652
 protein coding gene Chr13:105782251-105891805 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021297
 protein coding gene Chr13:110295469-110407546 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018867
 protein coding gene Chr13:98484471-98588479 (-)
CAST/EiJ MGP_CASTEiJ_G0020171
 protein coding gene Chr13:105303289-105408370 (-)
CBA/J MGP_CBAJ_G0020614
 protein coding gene Chr13:114577892-114699718 (-)
DBA/2J MGP_DBA2J_G0020738
 protein coding gene Chr13:102660999-102766533 (-)
FVB/NJ MGP_FVBNJ_G0020720
 protein coding gene Chr13:101363169-101465266 (-)
LP/J MGP_LPJ_G0020812
 protein coding gene Chr13:107108861-107218807 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020748
 protein coding gene Chr13:114833188-114944655 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021336
 protein coding gene Chr13:105517793-105624729 (-)
PWK/PhJ MGP_PWKPhJ_G0019924
 protein coding gene Chr13:101400613-101504856 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019747
 protein coding gene Chr13:101735138-101846273 (-)
WSB/EiJ MGP_WSBEiJ_G0020229
 protein coding gene Chr13:105985350-106095900 (-)



Homology
more
  • Human Ortholog
    RGS7BP, regulator of G protein signaling 7 binding protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RGS7BP, regulator of G protein signaling 7 binding protein
  • Synonyms
    R7BP
  • Links
    NCBI Gene ID: 401190
    neXtProt AC: NX_Q6MZT1
    UniProt: Q6MZT1

  • Chr Location
    5q12.3; chr5:64506015-64612319 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 2 genetic backgrounds
    15 phenotype references
Mice homozygous for a null allele exhibit normal behavior and brain morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    1
  • cDNA Data
    11
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52882 NCBI Gene Model | MGI Sequence Detail 109027 C57BL/6J ±  kb
transcript NM_029879 RefSeq | MGI Sequence Detail 5828 ZRU/MplStud  
polypeptide Q8BQP9 UniProt | EBI | MGI Sequence Detail 257 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-34026, MGI:1924468, MGI:2145292
References
more
  • Summaries
    All 49
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:281109 Song C, et al., The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex. J Biol Chem. 2019 Aug 30;294(35):13145-13157
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory