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Rad23a Gene Detail
Summary
  • Symbol
    Rad23a
  • Name
    RAD23 homolog A, nucleotide excision repair protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105126
    NCBI Gene: 19358
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85561540-85567361 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 41.20 cM, cytoband C3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105126
 protein coding gene Chr8:85560648-85567361 (-)
129S1/SvImJ ENSMUSG00200024134
 protein coding gene Chr8:79925969-79932628 (-)
A/J ENSMUSG00195014434
 protein coding gene Chr8:80284136-80290805 (-)
AKR/J ENSMUSG00220021826
 protein coding gene Chr8:80325547-80332206 (-)
BALB/cJ ENSMUSG00180019104
 protein coding gene Chr8:80124649-80131308 (-)
C3H/HeJ ENSMUSG00175010725
 protein coding gene Chr8:80219820-80226489 (-)
C57BL/6NJ ENSMUSG00215008693
 protein coding gene Chr8:79856939-79863585 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031310
 protein coding gene Chr8:76169403-76176083 (-)
CAST/EiJ ENSTCUG00005033478
 protein coding gene Chr8:79734249-79740903 (-)
CBA/J ENSMUSG00210020035
 protein coding gene Chr8:80206946-80213615 (-)
DBA/2J ENSMUSG00185036638
 protein coding gene Chr8:86315554-86322223 (-)
FVB/NJ ENSMUSG00205020482
 protein coding gene Chr8:79262765-79269434 (-)
JF1/MsJ ENSUMUG00000015414
 protein coding gene Chr8:88623442-88630088 (-)
LP/J ENSMUSG00230028742
 protein coding gene Chr8:89922969-89929628 (-)
NOD/ShiLtJ ENSMUSG00190026303
 protein coding gene Chr8:80283316-80289975 (-)
NZO/HlLtJ ENSMUSG00225039195
 protein coding gene Chr8:93317654-93324300 (-)
PWK/PhJ ENSLUMG00010027534
 protein coding gene Chr8:79960842-79967497 (-)
SPRET/EiJ ENSMSPG00010024330
 protein coding gene Chr8:81875529-81882175 (-)
WSB/EiJ ENSIUOG00005015620
 protein coding gene Chr8:81020891-81027550 (-)



Homology
more
  • Human Ortholog
    RAD23A, RAD23 nucleotide excision repair protein A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAD23A, RAD23 nucleotide excision repair protein A
  • Synonyms
    HHR23A, HR23A
  • Links
    NCBI Gene ID: 5886
    UniProt: P54725

  • Chr Location
    19p13.13; chr19:12945848-12953646 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 3 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    40 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Rad23a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Mice with a targeted disruption of this gene show no obvious phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    31
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19358 NCBI Gene Model | MGI Sequence Detail 5822 C57BL/6J ±  kb
transcript NM_001378896 RefSeq | MGI Sequence Detail 2268 C57BL/6  
polypeptide P54726 UniProt | EBI | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 14
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-32167, MGI:1916893, MGI:2142661
References
more
  • Summaries
    All 77
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 40
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:381016 Guo X, et al., Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy. Nat Commun. 2026 Jan 16;17(1):1820
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory