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Cct4 Gene Detail
Summary
  • Symbol
    Cct4
  • Name
    chaperonin containing TCP1 subunit 4
  • Synonyms
    2610204B21Rik, A45, Cctd, T complex protein 1, delta, TCP-1 delta
  • Feature Type
    protein coding gene
  • IDs
    MGI:104689
    NCBI Gene: 12464
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:22940593-22953336 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 14.25 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104689
 protein coding gene Chr11:22940519-22953780 (+)
129S1/SvImJ ENSMUSG00200021948
 protein coding gene Chr11:19957853-19971114 (+)
A/J ENSMUSG00195005195
 protein coding gene Chr11:19805225-19818486 (+)
AKR/J ENSMUSG00220003161
 protein coding gene Chr11:19894284-19907775 (+)
BALB/cJ ENSMUSG00180003866
 protein coding gene Chr11:19797371-19810639 (+)
C3H/HeJ ENSMUSG00175007904
 protein coding gene Chr11:19820256-19833527 (+)
C57BL/6NJ ENSMUSG00215003195
 protein coding gene Chr11:19884415-19897677 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016134
 protein coding gene Chr11:18815662-18830569 (+)
CAST/EiJ ENSTCUG00005007033
 protein coding gene Chr11:19786008-19799361 (+)
CBA/J ENSMUSG00210008848
 protein coding gene Chr11:19802112-19815384 (+)
DBA/2J ENSMUSG00185010848
 protein coding gene Chr11:19911758-19925027 (+)
FVB/NJ ENSMUSG00205004164
 protein coding gene Chr11:19855893-19869384 (+)
JF1/MsJ ENSUMUG00000008182
 protein coding gene Chr11:20124630-20138056 (+)
LP/J ENSMUSG00230013645
 protein coding gene Chr11:20947423-20960689 (+)
NOD/ShiLtJ ENSMUSG00190008387
 protein coding gene Chr11:19965450-19978723 (+)
NZO/HlLtJ ENSMUSG00225020516
 protein coding gene Chr11:22989684-23002945 (+)
PWK/PhJ ENSLUMG00010011478
 protein coding gene Chr11:19796725-19810143 (+)
SPRET/EiJ ENSMSPG00010018018
 protein coding gene Chr11:20044050-20057959 (+)
WSB/EiJ ENSIUOG00005009761
 protein coding gene Chr11:19865786-19879175 (+)



Homology
more
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
  • Synonyms
    Cctd, CCT-DELTA, SRB
  • Links
    NCBI Gene ID: 10575
    UniProt: P50991

  • Chr Location
    2p15; chr2:61868085-61888696 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    637
  • Tissues
    31
  • cDNA Data
    26
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12464 NCBI Gene Model | MGI Sequence Detail 12744 C57BL/6J ±  kb
transcript NM_009837 RefSeq | MGI Sequence Detail 1966 129/Sv  
polypeptide P80315 UniProt | EBI | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    Genomic 1
    cDNA 27
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-27052, MGI:1914415, MGI:2144639
References
more
  • Summaries
    All 60
    Developmental Gene Expression 2
    Gene Ontology 13
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:380488 Liu L, et al., Ubiquitin ligase subunit FBXO9 inhibits V-ATPase assembly and impedes lung cancer metastasis. Exp Hematol Oncol. 2024 Mar 14;13(1):32
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory