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Ube2h Gene Detail
Summary
  • Symbol
    Ube2h
  • Name
    ubiquitin-conjugating enzyme E2H
  • Synonyms
    1500009C23Rik, E2-20K, Gid3, Ubc8
  • Feature Type
    protein coding gene
  • IDs
    MGI:104632
    NCBI Gene: 22214
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:30211288-30304538 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 12.52 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    269 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104632
 protein coding gene Chr6:30211288-30304538 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030534
 protein coding gene Chr6:28072647-28172801 (-)
A/J MGP_AJ_G0030507
 protein coding gene Chr6:26867887-26965871 (-)
AKR/J MGP_AKRJ_G0030434
 protein coding gene Chr6:27750659-27863077 (-)
BALB/cJ MGP_BALBcJ_G0030517
 protein coding gene Chr6:27026464-27121066 (-)
C3H/HeJ MGP_C3HHeJ_G0030230
 protein coding gene Chr6:27754088-27855961 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030971
 protein coding gene Chr6:28882482-28986308 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028182
 protein coding gene Chr6:25074270-25169494 (-)
CAST/EiJ MGP_CASTEiJ_G0029632
 protein coding gene Chr6:27576895-27678010 (-)
CBA/J MGP_CBAJ_G0030208
 protein coding gene Chr6:29964843-30071566 (-)
DBA/2J MGP_DBA2J_G0030352
 protein coding gene Chr6:26805153-26898830 (-)
FVB/NJ MGP_FVBNJ_G0030306
 protein coding gene Chr6:26565993-26659344 (-)
LP/J MGP_LPJ_G0030439
 protein coding gene Chr6:28211007-28312518 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030342
 protein coding gene Chr6:32432280-32536451 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031001
 protein coding gene Chr6:27644350-27746793 (-)
PWK/PhJ MGP_PWKPhJ_G0029346
 protein coding gene Chr6:26367272-26464701 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029182
 protein coding gene Chr6:27384536-27481282 (-)
WSB/EiJ MGP_WSBEiJ_G0029708
 protein coding gene Chr6:27616926-27715863 (-)



Homology
more
  • Human Ortholog
    UBE2H, ubiquitin conjugating enzyme E2 H
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2H, ubiquitin conjugating enzyme E2 H
  • Synonyms
    E2-20K, GID3, UBC8, UBCH, UBCH2
  • Links
    NCBI Gene ID: 7328
    neXtProt AC: NX_P62256
    UniProt: P62256

  • Chr Location
    7q32.2; chr7:129830732-129952960 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    752
  • Tissues
    45
  • cDNA Data
    16
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 22214 NCBI Gene Model | MGI Sequence Detail 93251 C57BL/6J ±  kb
transcript NM_009459 RefSeq | MGI Sequence Detail 4657 ZRU/MplStud  
polypeptide P62257 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 16
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-26069, MGI:1917039, MGI:2141382, MGI:2141397, MGI:2141423, MGI:2141793, MGI:2144516
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:29209 Wefes I, et al., Characterization of a cDNA clone encoding E2-20K, a murine ubiquitin-conjugating enzyme. Gene. 1995 Oct 3;163(2):321-2
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory