About   Help   FAQ
Prpf39 Gene Detail
Summary
  • Symbol
    Prpf39
  • Name
    pre-mRNA processing factor 39
  • Synonyms
    MGC:37077, Srcs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104602
    NCBI Gene: 328110
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:65083107-65110160 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 27.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    108 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104602
 protein coding gene Chr12:65083094-65110160 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019778
 protein coding gene Chr12:64515693-64542741 (+)
A/J MGP_AJ_G0019737
 protein coding gene Chr12:62134044-62161422 (+)
AKR/J MGP_AKRJ_G0019712
 protein coding gene Chr12:64113728-64140780 (+)
BALB/cJ MGP_BALBcJ_G0019717
 protein coding gene Chr12:62575747-62602838 (+)
C3H/HeJ MGP_C3HHeJ_G0019522
 protein coding gene Chr12:64454945-64486885 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020169
 protein coding gene Chr12:66552541-66579965 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017789
 protein coding gene Chr12:59950196-59977756 (+)
CAST/EiJ MGP_CASTEiJ_G0019074
 protein coding gene Chr12:59162116-59193589 (+)
CBA/J MGP_CBAJ_G0019491
 protein coding gene Chr12:68976420-69006185 (+)
DBA/2J MGP_DBA2J_G0019607
 protein coding gene Chr12:62062427-62089528 (+)
FVB/NJ MGP_FVBNJ_G0019595
 protein coding gene Chr12:61088509-61116000 (+)
LP/J MGP_LPJ_G0019679
 protein coding gene Chr12:64534775-64564119 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019633
 protein coding gene Chr12:71840069-71873288 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020203
 protein coding gene Chr12:63501105-63528134 (+)
PWK/PhJ MGP_PWKPhJ_G0018840
 protein coding gene Chr12:56334938-56362534 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018634
 protein coding gene Chr12:57823219-57850989 (+)
WSB/EiJ MGP_WSBEiJ_G0019125
 protein coding gene Chr12:64032574-64059612 (+)



Homology
more
  • Human Ortholog
    PRPF39, pre-mRNA processing factor 39
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRPF39, pre-mRNA processing factor 39
  • Links
    NCBI Gene ID: 55015
    neXtProt AC: NX_Q86UA1
    UniProt: Q86UA1

  • Chr Location
    14q21.2; chr14:45084107-45116282 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035597 Ensembl Gene Model | MGI Sequence Detail 27054 C57BL/6J ±  kb
    transcript ENSMUST00000120580 Ensembl | MGI Sequence Detail 4069 Not Applicable  
    polypeptide ENSMUSP00000112953 Ensembl | MGI Sequence Detail 665 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-26038
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:22534 Frankfort BJ, et al., Identification of novel cellular genes transcriptionally suppressed by v-src. Biochem Biophys Res Commun. 1995 Jan 26;206(3):916-26
    • Latest
      J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory