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Pou6f1 Gene Detail
Summary
  • Symbol
    Pou6f1
  • Name
    POU domain, class 6, transcription factor 1
  • Synonyms
    2310038G18Rik, cns-1, Emb
  • Feature Type
    protein coding gene
  • IDs
    MGI:102935
    NCBI Gene: 19009
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100473199-100497865 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.35 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    813 from dbSNP Build 142
  • Strain Annotations
    20
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102935
 protein coding gene Chr15:100473199-100497949 (-)
129S1/SvImJ ENSMUSG00200051423
 protein coding gene Chr15:97680910-97686954 (-)
A/J ENSMUSG00195038734
 protein coding gene Chr15:97556575-97576291 (-)
AKR/J ENSMUSGG00220054347
 protein coding gene Chr15:97561114-97569505 (-)
AKR/J ENSMUSG00220044144
 protein coding gene Chr15:97549784-97558629 (-)
BALB/cJ ENSMUSG00180036372
 protein coding gene Chr15:97454631-97474353 (-)
C3H/HeJ ENSMUSG00175040921
 protein coding gene Chr15:97736554-97756274 (-)
C57BL/6NJ ENSMUSG00215050135
 protein coding gene Chr15:97511648-97520489 (-)
C57BL/6NJ ENSMUSGG00215055237
 protein coding gene Chr15:97522974-97531363 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020294
 protein coding gene Chr15:94265843-94290651 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210028890
 protein coding gene Chr15:97511470-97520272 (-)
DBA/2J ENSMUSG00185038241
 protein coding gene Chr15:97556200-97575916 (-)
FVB/NJ ENSMUSG00205027663
 protein coding gene Chr15:97260659-97269500 (-)
FVB/NJ ENSMUSGG00205054060
 protein coding gene Chr15:97271985-97280376 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230039661
 protein coding gene Chr15:100904241-100910285 (-)
NOD/ShiLtJ ENSMUSG00190047239
 protein coding gene Chr15:97487365-97507087 (-)
NZO/HlLtJ ENSMUSG00225041645
 protein coding gene Chr15:101105488-101114306 (-)
PWK/PhJ ENSLUMG00010038821
 protein coding gene Chr15:97217373-97237132 (-)
SPRET/EiJ ENSMSPG00010048505
 protein coding gene Chr15:99040307-99066407 (-)
WSB/EiJ ENSIUOG00005036050
 protein coding gene Chr15:97642507-97662250 (-)



Homology
more
  • Human Ortholog
    POU6F1, POU class 6 homeobox 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POU6F1, POU class 6 homeobox 1
  • Synonyms
    BRN5, MPOU, TCFB1
  • Links
    NCBI Gene ID: 5463
    UniProt: Q14863

  • Chr Location
    12q13.13; chr12:51186936-51218062 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    893
  • Tissues
    121
  • cDNA Data
    71
  • Literature Summary
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009739 Ensembl Gene Model | MGI Sequence Detail 24667 C57BL/6J ±  kb
transcript ENSMUST00000073837 Ensembl | MGI Sequence Detail 4953 Not Applicable  
polypeptide ENSMUSP00000073504 Ensembl | MGI Sequence Detail 576 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    Genomic 3
    cDNA 72
    Primer pair 1
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-23769, MGI:1914205, MGI:2146292
References
more
  • Summaries
    All 77
    Developmental Gene Expression 14
    Diseases 1
    Gene Ontology 8
    Phenotypes 28
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory