About   Help   FAQ
Tubg1 Gene Detail
Summary
  • Symbol
    Tubg1
  • Name
    tubulin, gamma 1
  • Synonyms
    1500010O08Rik, MGC:8041
  • Feature Type
    protein coding gene
  • IDs
    MGI:101834
    NCBI Gene: 103733
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101010764-101017245 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 64.24 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101834
protein coding gene Chr11:101010725-101017249 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019182
protein coding gene Chr11:103934357-103943739 (+)
A/J MGP_AJ_G0019150
protein coding gene Chr11:99578331-99584144 (+)
AKR/J MGP_AKRJ_G0019119
protein coding gene Chr11:102675248-102682637 (+)
BALB/cJ MGP_BALBcJ_G0019124
protein coding gene Chr11:100071493-100078605 (+)
C3H/HeJ MGP_C3HHeJ_G0018933
protein coding gene Chr11:102844320-102851561 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019573
protein coding gene Chr11:107157539-107164868 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017199
protein coding gene Chr11:96996680-97002881 (+)
CAST/EiJ MGP_CASTEiJ_G0018487
protein coding gene Chr11:103834301-103840994 (+)
CBA/J MGP_CBAJ_G0018902
protein coding gene Chr11:111616397-111626567 (+)
DBA/2J MGP_DBA2J_G0019014
protein coding gene Chr11:99111981-99118375 (+)
FVB/NJ MGP_FVBNJ_G0019004
protein coding gene Chr11:98655470-98661226 (+)
LP/J MGP_LPJ_G0019083
protein coding gene Chr11:104481498-104488346 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019035
protein coding gene Chr11:111179484-111185821 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019611
protein coding gene Chr11:102993630-103002781 (+)
PWK/PhJ MGP_PWKPhJ_G0018250
protein coding gene Chr11:100163335-100170103 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018042
protein coding gene Chr11:102733388-102739263 (+)
WSB/EiJ MGP_WSBEiJ_G0018536
protein coding gene Chr11:102996159-103002463 (+)



Homology
more
  • Human Ortholog
    TUBG1, tubulin gamma 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBG1, tubulin gamma 1
  • Synonyms
    CDCBM4, GCP-1, TUBG, TUBGCP1
  • Links
    NCBI Gene ID: 7283
    neXtProt AC: NX_P23258
    UniProt: P23258

  • Chr Location
    17q21.2; chr17:42609641-42615238 (+)  GRCh38

Human Diseases
more
  • Diseases
    3 with human TUBG1 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display embryonic lethality and growth arrest at the blastocyst stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035198 Ensembl Gene Model | MGI Sequence Detail 6482 C57BL/6J ±  kb
transcript ENSMUST00000043680 Ensembl | MGI Sequence Detail 1802 Not Applicable  
polypeptide ENSMUSP00000048036 Ensembl | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18655, MGI:1923590, MGI:2144173, MGI:2144203
References
more
  • Summaries
    All 230
    Developmental Gene Expression 163
    Gene Ontology 18
    Phenotypes 13
  • Earliest
    J:12193 Gueth-Hallonet C, et al., gamma-Tubulin is present in acentriolar MTOCs during early mouse development. J Cell Sci. 1993 May;105(Pt 1):157-66
  • Latest
    J:343451 Camblor-Perujo S, et al., The AP-2 complex interacts with gamma-TuRC and regulates the proliferative capacity of neural progenitors. Life Sci Alliance. 2024 Feb;7(2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory