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Adss1 Gene Detail
Summary
  • Symbol
    Adss1
  • Name
    adenylosuccinate synthase 1
  • Synonyms
    Adss, Adssl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:87947
    NCBI Gene: 11565
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:112586481-112607789 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    332 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_87947
 protein coding gene Chr12:112586479-112607794 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020154
 protein coding gene Chr12:115076524-115099740 (+)
A/J MGP_AJ_G0020110
 protein coding gene Chr12:110649161-110671228 (+)
AKR/J MGP_AKRJ_G0020085
 protein coding gene Chr12:113838786-113860173 (+)
BALB/cJ MGP_BALBcJ_G0020095
 protein coding gene Chr12:111092230-111113922 (+)
C3H/HeJ MGP_C3HHeJ_G0019897
 protein coding gene Chr12:114343850-114369055 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020540
 protein coding gene Chr12:118644450-118665733 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018153
 protein coding gene Chr12:107080028-107101920 (+)
CAST/EiJ MGP_CASTEiJ_G0019437
 protein coding gene Chr12:109190385-109211637 (+)
CBA/J MGP_CBAJ_G0019864
 protein coding gene Chr12:123178942-123204807 (+)
DBA/2J MGP_DBA2J_G0019981
 protein coding gene Chr12:110127790-110149058 (+)
FVB/NJ MGP_FVBNJ_G0019966
 protein coding gene Chr12:108951283-108975059 (+)
LP/J MGP_LPJ_G0020055
 protein coding gene Chr12:114902813-114926715 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020004
 protein coding gene Chr12:126264235-126285605 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020569
 protein coding gene Chr12:113361686-113383086 (+)
PWK/PhJ MGP_PWKPhJ_G0019199
 protein coding gene Chr12:104785664-104806972 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019002
 protein coding gene Chr12:107522599-107543359 (+)
WSB/EiJ MGP_WSBEiJ_G0019497
 protein coding gene Chr12:114269281-114292413 (+)



Homology
more
  • Human Ortholog
    ADSS1, adenylosuccinate synthase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADSS1, adenylosuccinate synthase 1
  • Synonyms
    ADSSL1, MPD5
  • Links
    NCBI Gene ID: 122622
    neXtProt AC: NX_Q8N142
    UniProt: Q8N142

  • Chr Location
    14q32.33; chr14:104724174-104747325 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    866
  • Tissues
    153
  • cDNA Data
    31
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11565 NCBI Gene Model | MGI Sequence Detail 21309 C57BL/6J ±  kb
transcript NM_007421 RefSeq | MGI Sequence Detail 1806 C57BL/6  
polypeptide P28650 UniProt | EBI | MGI Sequence Detail 457 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    Genomic 5
    cDNA 32
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-1163, MGD-MRK-1164, MGI:2144855
References
more
  • Summaries
    All 43
    Developmental Gene Expression 8
    Gene Ontology 12
    Phenotypes 5
  • Earliest
    J:11538 Guicherit OM, et al., Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase. J Biol Chem. 1991 Nov 25;266(33):22582-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory