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Rft1 Gene Detail
Summary
  • Symbol
    Rft1
  • Name
    RFT1 homolog
  • Feature Type
    protein coding gene
  • IDs
    MGI:3607791
    NCBI Gene: 328370
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30376317-30413274 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 18.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3607791
protein coding gene Chr14:30375041-30413274 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021106
protein coding gene Chr14:23788863-23827842 (+)
A/J MGP_AJ_G0021054
protein coding gene Chr14:22906847-22944248 (+)
AKR/J MGP_AKRJ_G0021031
protein coding gene Chr14:24016061-24055387 (+)
BALB/cJ MGP_BALBcJ_G0021058
protein coding gene Chr14:23004914-23042429 (+)
C3H/HeJ MGP_C3HHeJ_G0020841
protein coding gene Chr14:23873381-23911721 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021490
protein coding gene Chr14:24736206-24779956 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019053
protein coding gene Chr14:22963734-23002582 (+)
CAST/EiJ MGP_CASTEiJ_G0020366
protein coding gene Chr14:23617040-23659100 (+)
CBA/J MGP_CBAJ_G0020808
protein coding gene Chr14:25690060-25731310 (+)
DBA/2J MGP_DBA2J_G0020930
protein coding gene Chr14:22939593-22976205 (+)
FVB/NJ MGP_FVBNJ_G0020914
protein coding gene Chr14:22893610-22930961 (+)
LP/J MGP_LPJ_G0020999
protein coding gene Chr14:24111919-24149778 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020940
protein coding gene Chr14:24977941-25016403 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021523
protein coding gene Chr14:23761801-23797750 (+)
PWK/PhJ MGP_PWKPhJ_G0020114
protein coding gene Chr14:22374000-22411695 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019938
protein coding gene Chr14:23352492-23393238 (+)
WSB/EiJ MGP_WSBEiJ_G0020421
protein coding gene Chr14:23824496-23862407 (+)



Homology
more
  • Human Ortholog
    RFT1, RFT1 homolog
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RFT1, RFT1 homolog
  • Synonyms
    CDG1N
  • Links
    NCBI Gene ID: 91869
    neXtProt AC: NX_Q96AA3
    UniProt: Q96AA3

  • Chr Location
    3p21.1; chr3:53066853-53130453 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human RFT1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000052395 Ensembl Gene Model | MGI Sequence Detail 36958 C57BL/6J ±  kb
    transcript ENSMUST00000064230 Ensembl | MGI Sequence Detail 2387 Not Applicable  
    polypeptide ENSMUSP00000064153 Ensembl | MGI Sequence Detail 541 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 1
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory