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Ccdc63 Gene Detail
Summary
  • Symbol
    Ccdc63
  • Name
    coiled-coil domain containing 63
  • Synonyms
    4921511C16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3607777
    NCBI Gene: 330188
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:122246115-122276143 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    957 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3607777
 protein coding gene Chr5:122246103-122278886 (-)
129S1/SvImJ ENSMUSG00200025201
 protein coding gene Chr5:115986060-116015894 (-)
A/J ENSMUSG00195010867
 protein coding gene Chr5:115507343-115537181 (-)
AKR/J ENSMUSG00220036056
 protein coding gene Chr5:115007496-115037538 (-)
BALB/cJ ENSMUSG00180033378
 protein coding gene Chr5:115621930-115651764 (-)
C3H/HeJ ENSMUSG00175028168
 protein coding gene Chr5:117627489-117657524 (-)
C57BL/6NJ ENSMUSG00215028637
 protein coding gene Chr5:115653253-115683289 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027697
 protein coding gene Chr5:115139945-115173180 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210006518
 protein coding gene Chr5:116378331-116408364 (-)
DBA/2J ENSMUSG00185048511
 protein coding gene Chr5:119429528-119459557 (-)
FVB/NJ ENSMUSG00205029231
 protein coding gene Chr5:115283093-115313117 (-)
JF1/MsJ ENSUMUG00000049309
 protein coding gene Chr5:122285313-122315265 (-)
LP/J ENSMUSG00230043183
 protein coding gene Chr5:123508120-123537952 (-)
NOD/ShiLtJ ENSMUSG00190030489
 protein coding gene Chr5:115320074-115350110 (-)
NZO/HlLtJ ENSMUSG00225015847
 protein coding gene Chr5:131186353-131216382 (-)
PWK/PhJ ENSLUMG00010033977
 protein coding gene Chr5:114194507-114224303 (-)
SPRET/EiJ ENSMSPG00010039079
 protein coding gene Chr5:117514322-117541551 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CCDC63, coiled-coil domain containing 63
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC63, coiled-coil domain containing 63
  • Synonyms
    ODA5
  • Links
    NCBI Gene ID: 160762
    UniProt: Q8NA47

  • Chr Location
    12q24.11; chr12:110844486-110907535 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility, defects in sperm heads and impaired elongation of flagella with no motile spermatozoa.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 330188 NCBI Gene Model | MGI Sequence Detail 30029 C57BL/6J ±  kb
    transcript NM_183307 RefSeq | MGI Sequence Detail 2287 C57BL/6  
    polypeptide Q8CDV6 UniProt | EBI | MGI Sequence Detail 558 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000032175 coiled-coil domain-containing protein 63
      (term hierarchy)
    • InterPro Domains
      IPR049258 ODAD1, central coiled coil region
      IPR051876 Outer dynein arm-docking/Coiled-coil domain-containing protein
    • GlyGen
      Q8CDV6 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Gene Ontology 2
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:231237 Young SA, et al., CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis. Int J Mol Sci. 2015;16(10):24732-50
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory