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Fbxl7 Gene Detail
Summary
  • Symbol
    Fbxl7
  • Name
    F-box and leucine-rich repeat protein 7
  • Synonyms
    D230018M15Rik, Fbl6, FBL7
  • Feature Type
    protein coding gene
  • IDs
    MGI:3052506
    NCBI Gene: 448987
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:26540540-26895650 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 9.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10893 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3052506
 protein coding gene Chr15:26540540-26895666 (-)
129S1/SvImJ ENSMUSG00200027592
 protein coding gene Chr15:23536245-23893117 (-)
A/J ENSMUSG00195013807
 protein coding gene Chr15:23497987-23853567 (-)
AKR/J ENSMUSG00220046866
 protein coding gene Chr15:23352318-23707481 (-)
BALB/cJ ENSMUSG00180005302
 protein coding gene Chr15:23432156-23787324 (-)
C3H/HeJ ENSMUSG00175004479
 protein coding gene Chr15:23587399-23942978 (-)
C57BL/6NJ ENSMUSG00215004971
 protein coding gene Chr15:23488254-23843420 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019700
 protein coding gene Chr15:21938567-22330124 (-)
CAST/EiJ ENSTCUG00005014706
 protein coding gene Chr15:23542538-23895413 (-)
CBA/J ENSMUSG00210024174
 protein coding gene Chr15:23534197-23889763 (-)
DBA/2J ENSMUSG00185023447
 protein coding gene Chr15:23526767-23882340 (-)
FVB/NJ ENSMUSG00205013500
 protein coding gene Chr15:23480318-23835736 (-)
JF1/MsJ ENSUMUG00000011871
 protein coding gene Chr15:23529256-23893204 (-)
LP/J ENSMUSG00230014004
 protein coding gene Chr15:27005831-27362660 (-)
NOD/ShiLtJ ENSMUSG00190011811
 protein coding gene Chr15:23505895-23861031 (-)
NZO/HlLtJ ENSMUSG00225031685
 protein coding gene Chr15:27248209-27603357 (-)
PWK/PhJ ENSLUMG00010021685
 protein coding gene Chr15:23652405-24016949 (-)
SPRET/EiJ ENSMSPG00010022325
 protein coding gene Chr15:24087228-24451732 (-)
WSB/EiJ ENSIUOG00005020129
 protein coding gene Chr15:23532711-23892855 (-)



Homology
more
  • Human Ortholog
    FBXL7, F-box and leucine rich repeat protein 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXL7, F-box and leucine rich repeat protein 7
  • Synonyms
    FBL6, FBL7
  • Links
    NCBI Gene ID: 23194
    UniProt: Q9UJT9

  • Chr Location
    5p15.1; chr5:15500180-15939795 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    23
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 448987 NCBI Gene Model | MGI Sequence Detail 355111 C57BL/6J ±  kb
transcript NM_176959 RefSeq | MGI Sequence Detail 4639 C57BL/6  
polypeptide Q5BJ29 UniProt | EBI | MGI Sequence Detail 491 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007385 F-box/LRR-repeat protein 7
    (term hierarchy)
  • InterPro Domains
    IPR001810 F-box domain
    IPR036047 F-box-like domain superfamily
    IPR057207 F-box/LRR-repeat protein 15-like, leucin rich repeat domain
    IPR006553 Leucine-rich repeat, cysteine-containing subtype
    IPR032675 Leucine-rich repeat domain superfamily
  • GlyGen
    Q5BJ29 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 7
Other
Accession IDs
less
MGI:2146117, MGI:2442376
References
more
  • Summaries
    All 40
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory