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H3c1 Gene Detail
Summary
  • Symbol
    H3c1
  • Name
    H3 clustered histone 1
  • Synonyms
    Hist1h3a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2668828
    NCBI Gene: 360198
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23945868-23946369 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2668828
 protein coding gene Chr13:23945836-23946369 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020366
 protein coding gene Chr13:21205757-21207436 (-)
A/J MGP_AJ_G0020315
 protein coding gene Chr13:20815006-20816335 (-)
AKR/J MGP_AKRJ_G0020295
 protein coding gene Chr13:21068654-21069187 (-)
BALB/cJ MGP_BALBcJ_G0020313
 protein coding gene Chr13:20811477-20812010 (-)
C3H/HeJ MGP_C3HHeJ_G0020117
 protein coding gene Chr13:21141231-21141764 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020750
 protein coding gene Chr13:21985879-21987200 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018338
 protein coding gene Chr13:19588803-19589330 (-)
CAST/EiJ MGP_CASTEiJ_G0026774
 protein coding gene Chr3:95903419-95904033 (-)
CBA/J MGP_CBAJ_G0020071
 protein coding gene Chr13:22842727-22845019 (-)
DBA/2J MGP_DBA2J_G0020197
 protein coding gene Chr13:20343084-20344000 (-)
FVB/NJ MGP_FVBNJ_G0020181
 protein coding gene Chr13:19994745-19995542 (-)
LP/J MGP_LPJ_G0020270
 protein coding gene Chr13:21515052-21516479 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020208
 protein coding gene Chr13:23135887-23136420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020792
 protein coding gene Chr13:20921333-20921866 (-)
PWK/PhJ MGP_PWKPhJ_G0019388
 protein coding gene Chr13:20374759-20375467 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019205
 protein coding gene Chr13:19726947-19727470 (-)
WSB/EiJ MGP_WSBEiJ_G0019694
 protein coding gene Chr13:21058558-21059926 (-)



Homology
more
  • Human Ortholog
    H3C1, H3 clustered histone 1
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H3C1, H3 clustered histone 1
  • Synonyms
    H3/A, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, HIST1H3A
  • Links
    NCBI Gene ID: 8350
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26020451-26020958 (+)  GRCh38
  • Human Ortholog
    H3C10, H3 clustered histone 10
  • Synonyms
    H3C1, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3F1K, H3FK, H3/k, HIST1H3H
  • Links
    NCBI Gene ID: 8357
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.1; chr6:27810051-27811300 (+)  GRCh38
  • Human Ortholog
    H3C11, H3 clustered histone 11
  • Synonyms
    H3C1, H3C10, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3/f, H3.f, H3FF, HIST1H3I
  • Links
    NCBI Gene ID: 8354
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.1; chr6:27871845-27872346 (-)  GRCh38
  • Human Ortholog
    H3C2, H3 clustered histone 2
  • Synonyms
    H3C1, H3C10, H3C11, H3C12, H3C3, H3C4, H3C6, H3C7, H3C8, H3FL, H3/l, HIST1H3B
  • Links
    NCBI Gene ID: 8358
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26031589-26032099 (-)  GRCh38
  • Human Ortholog
    H3C3, H3 clustered histone 3
  • Synonyms
    H3.1, H3/c, H3C1, H3C10, H3C11, H3C12, H3C2, H3C4, H3C6, H3C7, H3C8, H3FC, HIST1H3C
  • Links
    NCBI Gene ID: 8352
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26045384-26045869 (+)  GRCh38
  • Human Ortholog
    H3C4, H3 clustered histone 4
  • Synonyms
    H3/b, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C6, H3C7, H3C8, H3FB, HIST1H3D
  • Links
    NCBI Gene ID: 8351
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26196784-26199293 (-)  GRCh38
  • Human Ortholog
    H3C8, H3 clustered histone 8
  • Synonyms
    H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3FH, H3/h, HIST1H3G
  • Links
    NCBI Gene ID: 8355
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26270918-26271413 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 360198 NCBI Gene Model | MGI Sequence Detail 502 C57BL/6J ±  kb
transcript NM_013550 RefSeq | MGI Sequence Detail 502 C57BL/6  
polypeptide P68433 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:278064 Tsuji-Hosokawa A, et al., Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development. Sci Rep. 2018 Sep 5;8(1):13263
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory