About   Help   FAQ
Zfp637 Gene Detail
Summary
  • Symbol
    Zfp637
  • Name
    zinc finger protein 637
  • Synonyms
    MGC:54806
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448537
    NCBI Gene: 232337
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:117818165-117822917 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 55.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448537
 protein coding gene Chr6:117818141-117822917 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031178
 protein coding gene Chr6:120551556-120556332 (+)
A/J MGP_AJ_G0031148
 protein coding gene Chr6:115948236-115953176 (+)
AKR/J MGP_AKRJ_G0031078
 protein coding gene Chr6:119061835-119066604 (+)
BALB/cJ MGP_BALBcJ_G0031158
 protein coding gene Chr6:115720706-115725497 (+)
C3H/HeJ MGP_C3HHeJ_G0030551
 protein coding gene Chr6:65236651-65241436 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031616
 protein coding gene Chr6:123654406-123661017 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030265
 protein coding gene Chr6:119430215-119434926 (+)
CBA/J MGP_CBAJ_G0030842
 protein coding gene Chr6:128531571-128536348 (+)
DBA/2J MGP_DBA2J_G0030998
 protein coding gene Chr6:114849038-114853814 (+)
FVB/NJ MGP_FVBNJ_G0030950
 protein coding gene Chr6:113979867-113984645 (+)
LP/J MGP_LPJ_G0031076
 protein coding gene Chr6:120580913-120585682 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030984
 protein coding gene Chr6:132654198-132658978 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031645
 protein coding gene Chr6:119092746-119097517 (+)
PWK/PhJ MGP_PWKPhJ_G0029981
 protein coding gene Chr6:113850880-113856128 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029809
 protein coding gene Chr6:117795574-117800230 (+)
WSB/EiJ MGP_WSBEiJ_G0030348
 protein coding gene Chr6:119353786-119358662 (+)



Homology
more
  • Human Ortholog
    ZNF32, zinc finger protein 32
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF32, zinc finger protein 32
  • Synonyms
    KOX30, Zfp637, ZNF637
  • Links
    NCBI Gene ID: 7580
    neXtProt AC: NX_P17041
    UniProt: P17041

  • Chr Location
    10q11.21; chr10:43643860-43648881 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele do not display any obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    5
  • cDNA Data
    53
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232337 NCBI Gene Model | MGI Sequence Detail 4753 C57BL/6J ±  kb
    transcript NM_001411614 RefSeq | MGI Sequence Detail 1522 C57BL/6  
    polypeptide Q80V23 UniProt | EBI | MGI Sequence Detail 272 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 54
      cDNA 54

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141459
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 9
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:295189 Marenne G, et al., Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. Cell Metab. 2020 Jun 2;31(6):1107-1119.e12
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory