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Dpy19l2 Gene Detail
Summary
  • Symbol
    Dpy19l2
  • Name
    dpy-19 like 2
  • Synonyms
    4932443J21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444662
    NCBI Gene: 320752
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:24468343-24607589 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 10.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3889 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444662
 protein coding gene Chr9:24468343-24607752 (-)
129S1/SvImJ ENSMUSG00200008080
 protein coding gene Chr9:21445197-21584448 (-)
A/J ENSMUSG00195005842
 protein coding gene Chr9:21261583-21400856 (-)
AKR/J ENSMUSG00220010185
 protein coding gene Chr9:21260506-21399782 (-)
BALB/cJ ENSMUSG00180006723
 protein coding gene Chr9:21395795-21535061 (-)
C3H/HeJ ENSMUSG00175018694
 protein coding gene Chr9:21372251-21511514 (-)
C57BL/6NJ ENSMUSG00215006792
 protein coding gene Chr9:21357561-21496805 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031914
 protein coding gene Chr9:20519889-20581677 (-)
CAST/EiJ ENSTCUG00005018610
 protein coding gene Chr9:21359308-21494848 (-)
CBA/J ENSMUSG00210022033
 protein coding gene Chr9:21378628-21524085 (-)
DBA/2J ENSMUSG00185002292
 protein coding gene Chr9:21454429-21593686 (-)
FVB/NJ ENSMUSG00205003920
 protein coding gene Chr9:21702153-21847604 (-)
JF1/MsJ ENSUMUG00000008912
 protein coding gene Chr9:21558460-21700315 (-)
LP/J ENSMUSG00230004659
 protein coding gene Chr9:21854290-21993540 (-)
NOD/ShiLtJ ENSMUSG00190005749
 protein coding gene Chr9:21399167-21544609 (-)
NZO/HlLtJ ENSMUSG00225014469
 protein coding gene Chr9:21828801-21974275 (-)
PWK/PhJ ENSLUMG00010008787
 protein coding gene Chr9:21448539-21589193 (-)
SPRET/EiJ ENSMSPG00010002021
 protein coding gene Chr9:21709549-21871536 (-)
WSB/EiJ ENSIUOG00005015526
 protein coding gene Chr9:20924772-21070986 (-)



Homology
more
  • Human Ortholog
    DPY19L2, dpy-19 like 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DPY19L2, dpy-19 like 2
  • Synonyms
    SPATA34, SPGF9
  • Links
    NCBI Gene ID: 283417
    UniProt: Q6NUT2

  • Chr Location
    12q14.2; chr12:63558913-63668939 (-)  GRCh38
  • Human Ortholog
    DPY19L2P1, DPY19L2 pseudogene 1
  • Links
    NCBI Gene ID: 554236
    UniProt: Q6NXN4

  • Chr Location
    7p14.2; chr7:35079989-35186175 (-)  GRCh38
  • Human Ortholog
    DPY19L2P2, DPY19L2 pseudogene 2
  • Links
    NCBI Gene ID: 349152
    UniProt: Q6ZN68

  • Chr Location
    7q22.1; chr7:103175013-103281293 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DPY19L2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit male sterility associated with globozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000085576 Ensembl Gene Model | MGI Sequence Detail 139247 C57BL/6J ±  kb
    transcript ENSMUST00000133010 Ensembl | MGI Sequence Detail 3442 Not Applicable  
    polypeptide ENSMUSP00000132092 Ensembl | MGI Sequence Detail 773 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 4
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 6
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:326789 Zhang XZ, et al., The perinuclear theca protein Calicin helps shape the sperm head and maintain the nuclear structure in mice. Cell Rep. 2022 Jul 5;40(1):111049
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory