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Ppp2r3a Gene Detail
Summary
  • Symbol
    Ppp2r3a
  • Name
    protein phosphatase 2, regulatory subunit B'', alpha
  • Synonyms
    3222402P14Rik, C530025M11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442104
    NCBI Gene: 235542
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:100982283-101128994 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 53.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1287 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442104
 protein coding gene Chr9:100982188-101129031 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035182
 protein coding gene Chr9:102587562-102739826 (-)
A/J MGP_AJ_G0035163
 protein coding gene Chr9:98952749-99094838 (-)
AKR/J MGP_AKRJ_G0035095
 protein coding gene Chr9:101359195-101503628 (-)
BALB/cJ MGP_BALBcJ_G0035156
 protein coding gene Chr9:98640048-98784655 (-)
C3H/HeJ MGP_C3HHeJ_G0034866
 protein coding gene Chr9:101794980-101940183 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035676
 protein coding gene Chr9:105517773-105670677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032575
 protein coding gene Chr9:96586645-96719787 (-)
CAST/EiJ MGP_CASTEiJ_G0034177
 protein coding gene Chr9:101598784-101744821 (-)
CBA/J MGP_CBAJ_G0034834
 protein coding gene Chr9:109186806-109338063 (-)
DBA/2J MGP_DBA2J_G0034996
 protein coding gene Chr9:98437934-98581462 (-)
FVB/NJ MGP_FVBNJ_G0034944
 protein coding gene Chr9:97242513-97385639 (-)
LP/J MGP_LPJ_G0035072
 protein coding gene Chr9:102805087-102958649 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034983
 protein coding gene Chr9:111066594-111175738 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035698
 protein coding gene Chr9:101632201-101777498 (-)
PWK/PhJ MGP_PWKPhJ_G0033884
 protein coding gene Chr9:98677733-98813548 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033720
 protein coding gene Chr9:101675599-101811776 (-)
WSB/EiJ MGP_WSBEiJ_G0034297
 protein coding gene Chr9:101508236-101652482 (-)



Homology
more
  • Human Ortholog
    PPP2R3A, protein phosphatase 2 regulatory subunit B''alpha
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP2R3A, protein phosphatase 2 regulatory subunit B''alpha
  • Synonyms
    PPP2R3, PR130, PR72
  • Links
    NCBI Gene ID: 5523
    neXtProt AC: NX_Q06190
    UniProt: Q06190

  • Chr Location
    3q22.2-q22.3; chr3:135965728-136147894 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    18
  • cDNA Data
    17
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000043154 Ensembl Gene Model | MGI Sequence Detail 146712 C57BL/6J ±  kb
    transcript ENSMUST00000075941 Ensembl | MGI Sequence Detail 6786 Not Applicable  
    polypeptide ENSMUSP00000075327 Ensembl | MGI Sequence Detail 1150 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000013139 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
      (term hierarchy)
    • InterPro Domains
      IPR018247 EF-Hand 1, calcium-binding site
      IPR002048 EF-hand domain
      IPR011992 EF-hand domain pair
      IPR041534 PP2A regulatory subunit B'', EF-hand domain
      IPR048855 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha/beta/delta, EF-hand
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 18
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2441907
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/23/2024
    MGI 6.23     		The Jackson Laboratory