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Pcmtd1 Gene Detail
Summary
  • Symbol
    Pcmtd1
  • Name
    protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
  • Synonyms
    8430411F12Rik, A030012M09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441773
    NCBI Gene: 319263
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:7159144-7243852 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441773
 protein coding gene Chr1:7157301-7243852 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015821
 protein coding gene Chr1:4330150-4419752 (+)
A/J MGP_AJ_G0015803
 protein coding gene Chr1:4261428-4347879 (+)
AKR/J MGP_AKRJ_G0015762
 protein coding gene Chr1:4239507-4335160 (+)
BALB/cJ MGP_BALBcJ_G0015759
 protein coding gene Chr1:4127415-4214211 (+)
C3H/HeJ MGP_C3HHeJ_G0015593
 protein coding gene Chr1:4212649-4308228 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016211
 protein coding gene Chr1:4439612-4545522 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013933
 protein coding gene Chr1:3639748-3722673 (+)
CAST/EiJ MGP_CASTEiJ_G0015173
 protein coding gene Chr1:4404603-4509872 (+)
CBA/J MGP_CBAJ_G0015566
 protein coding gene Chr1:4596026-4684948 (+)
DBA/2J MGP_DBA2J_G0015665
 protein coding gene Chr1:4076020-4162226 (+)
FVB/NJ MGP_FVBNJ_G0015670
 protein coding gene Chr1:4009415-4097936 (+)
LP/J MGP_LPJ_G0015738
 protein coding gene Chr1:4403103-4491808 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015689
 protein coding gene Chr1:4903282-5002279 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016258
 protein coding gene Chr1:4191642-4285054 (+)
PWK/PhJ MGP_PWKPhJ_G0014957
 protein coding gene Chr1:3964882-4044897 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014737
 protein coding gene Chr1:4397803-4488386 (+)
WSB/EiJ MGP_WSBEiJ_G0015237
 protein coding gene Chr1:4134002-4227289 (+)



Homology
more
  • Human Ortholog
    PCMTD1, protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCMTD1, protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
  • Links
    NCBI Gene ID: 115294
    neXtProt AC: NX_Q96MG8
    UniProt: Q96MG8

  • Chr Location
    8q11.23; chr8:51817575-51899186 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    856
  • Tissues
    21
  • cDNA Data
    20
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051285 Ensembl Gene Model | MGI Sequence Detail 84709 C57BL/6J ±  kb
transcript ENSMUST00000061280 Ensembl | MGI Sequence Detail 5232 Not Applicable  
polypeptide ENSMUSP00000059261 Ensembl | MGI Sequence Detail 357 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000032433 protein-L-isoaspartate O-methyltransferase domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Other 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1918705
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:307672 Knupp D, et al., NOVA2 regulates neural circRNA biogenesis. Nucleic Acids Res. 2021 Jul 9;49(12):6849-6862
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory