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Caln1 Gene Detail
Summary
  • Symbol
    Caln1
  • Name
    calneuron 1
  • Synonyms
    9630012C17Rik, Cabp8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2155987
    NCBI Gene: 140904
  • Alliance
    genome feature page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:130398296-130876253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 69.29 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14300 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2155987
 protein coding gene Chr5:130398245-130876253 (+)
129S1/SvImJ ENSMUSG00200041192
 protein coding gene Chr5:124143875-124631387 (+)
A/J ENSMUSG00195049013
 protein coding gene Chr5:123686353-124164840 (+)
AKR/J ENSMUSG00220044452
 protein coding gene Chr5:123154578-123632986 (+)
BALB/cJ ENSMUSG00180034553
 protein coding gene Chr5:123793693-124272138 (+)
C3H/HeJ ENSMUSG00175034366
 protein coding gene Chr5:125754130-126232429 (+)
C57BL/6NJ ENSMUSG00215045078
 protein coding gene Chr5:123826985-124305342 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027802
 protein coding gene Chr5:123208483-123686408 (+)
CAST/EiJ ENSTCUG00005009928
 protein coding gene Chr5:123064013-123542861 (+)
CBA/J ENSMUSG00210007305
 protein coding gene Chr5:124504828-124983141 (+)
DBA/2J ENSMUSG00185007447
 protein coding gene Chr5:127556790-128035328 (+)
FVB/NJ ENSMUSG00205044524
 protein coding gene Chr5:123436466-123919289 (+)
JF1/MsJ ENSUMUG00000049588
 protein coding gene Chr5:130452242-130932384 (+)
LP/J ENSMUSG00230047064
 protein coding gene Chr5:131659729-132146947 (+)
NOD/ShiLtJ ENSMUSG00190038782
 protein coding gene Chr5:123468826-123970685 (+)
NZO/HlLtJ ENSMUSG00225013820
 protein coding gene Chr5:139355286-139833057 (+)
PWK/PhJ ENSLUMG00010018159
 protein coding gene Chr5:122337240-122820530 (+)
SPRET/EiJ ENSMSPG00010026313
 protein coding gene Chr5:125752054-126236481 (+)
WSB/EiJ ENSIUOG00005030309
 protein coding gene Chr5:126138511-126613045 (+)



Homology
more
  • Human Ortholog
    CALN1, calneuron 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALN1, calneuron 1
  • Synonyms
    CABP8
  • Links
    NCBI Gene ID: 83698
    UniProt: Q9BXU9

  • Chr Location
    7q11.22; chr7:71779491-72504279 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit fewer Golgi satellites and decreased levels of polysialylation of NCAM in distal dendrites of hippocampal CA1 neurons that receive input from the temporoammonic pathway and reduced long-term potentiation at distal synapses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    656
  • Tissues
    35
  • cDNA Data
    13
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000060371 Ensembl Gene Model | MGI Sequence Detail 477958 C57BL/6J ±  kb
    transcript ENSMUST00000086029 Ensembl | MGI Sequence Detail 1801 Not Applicable  
    polypeptide ENSMUSP00000083193 Ensembl | MGI Sequence Detail 261 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2444767
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 3
      Gene Ontology 9
      Phenotypes 11
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:380149 Oelschlegel AM, et al., Elevated calneuron-1, an accessory subunit of muscarinic receptors, induces frontotemporal dysconnectivity and schizophrenia-like deficits. Neuron. 2026 Feb 18;114(4):679-698.e11
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory