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Nat10 Gene Detail
Summary
  • Symbol
    Nat10
  • Name
    N-acetyltransferase 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138939
    NCBI Gene: 98956
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:103551601-103591615 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 54.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138939
 protein coding gene Chr2:103551601-103593292 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026206
 protein coding gene Chr2:105710360-105750457 (-)
A/J MGP_AJ_G0026167
 protein coding gene Chr2:101352737-101391849 (-)
AKR/J MGP_AKRJ_G0026148
 protein coding gene Chr2:104102138-104143642 (-)
BALB/cJ MGP_BALBcJ_G0026176
 protein coding gene Chr2:101643579-101685803 (-)
C3H/HeJ MGP_C3HHeJ_G0025927
 protein coding gene Chr2:104440652-104484123 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026627
 protein coding gene Chr2:109248371-109291704 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024018
 protein coding gene Chr2:97029704-97071121 (-)
CAST/EiJ MGP_CASTEiJ_G0025392
 protein coding gene Chr2:104915228-104957175 (-)
CBA/J MGP_CBAJ_G0025905
 protein coding gene Chr2:112975669-113018463 (-)
DBA/2J MGP_DBA2J_G0026042
 protein coding gene Chr2:100915065-100954409 (-)
FVB/NJ MGP_FVBNJ_G0026004
 protein coding gene Chr2:99912950-99952921 (-)
LP/J MGP_LPJ_G0026145
 protein coding gene Chr2:105843387-105887573 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026030
 protein coding gene Chr2:116912126-116953086 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026681
 protein coding gene Chr2:104316184-104356702 (-)
PWK/PhJ MGP_PWKPhJ_G0025127
 protein coding gene Chr2:100427392-100467588 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024928
 protein coding gene Chr2:103531075-103572435 (-)
WSB/EiJ MGP_WSBEiJ_G0025459
 protein coding gene Chr2:105020834-105063202 (-)



Homology
more
  • Human Ortholog
    NAT10, N-acetyltransferase 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NAT10, N-acetyltransferase 10
  • Synonyms
    ALP, Kre33, NET43
  • Links
    NCBI Gene ID: 55226
    neXtProt AC: NX_Q9H0A0
    UniProt: Q9H0A0

  • Chr Location
    11p13; chr11:34105617-34147670 (+)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    29
  • cDNA Data
    17
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027185 Ensembl Gene Model | MGI Sequence Detail 40015 C57BL/6J ±  kb
    transcript ENSMUST00000028608 Ensembl | MGI Sequence Detail 3879 Not Applicable  
    polypeptide ENSMUSP00000028608 Ensembl | MGI Sequence Detail 1024 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 17
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 7
      Phenotypes 16
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345384 Zhang M, et al., The Cytidine N-Acetyltransferase NAT10 Participates in Peripheral Nerve Injury-Induced Neuropathic Pain by Stabilizing SYT9 Expression in Primary Sensory Neurons. J Neurosci. 2023 Apr 26;43(17):3009-3027
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory