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Pcdhb2 Gene Detail
Summary
  • Symbol
    Pcdhb2
  • Name
    protocadherin beta 2
  • Synonyms
    PcdhbB
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136735
    NCBI Gene: 93873
  • Member of
    Pcdhb cluster
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr18:37427893-37430667 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.46 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136735
 protein coding gene Chr18:37427865-37430677 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024311
 protein coding gene Chr18:35689148-35691961 (+)
A/J MGP_AJ_G0024278
 protein coding gene Chr18:34482341-34485154 (+)
AKR/J MGP_AKRJ_G0024246
 protein coding gene Chr18:35434428-35438218 (+)
BALB/cJ MGP_BALBcJ_G0024277
 protein coding gene Chr18:34511285-34514098 (+)
C3H/HeJ MGP_C3HHeJ_G0024044
 protein coding gene Chr18:35496266-35499080 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024719
 protein coding gene Chr18:36985093-36987905 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022158
 protein coding gene Chr18:34540885-34543687 (+)
CAST/EiJ MGP_CASTEiJ_G0023519
 protein coding gene Chr18:35460143-35462955 (+)
CBA/J MGP_CBAJ_G0024013
 protein coding gene Chr18:38074107-38076920 (+)
DBA/2J MGP_DBA2J_G0024143
 protein coding gene Chr18:34072836-34075649 (+)
FVB/NJ MGP_FVBNJ_G0024110
 protein coding gene Chr18:33792856-33795669 (+)
LP/J MGP_LPJ_G0024227
 protein coding gene Chr18:35780284-35783097 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024140
 protein coding gene Chr18:39339103-39341917 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024768
 protein coding gene Chr18:35290321-35293134 (+)
PWK/PhJ MGP_PWKPhJ_G0023263
 protein coding gene Chr18:34308638-34311565 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023069
 protein coding gene Chr18:35537911-35540715 (+)
WSB/EiJ MGP_WSBEiJ_G0023582
 protein coding gene Chr18:35190638-35193451 (+)



Homology
more
  • Human Ortholog
    PCDHB2, protocadherin beta 2
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB2, protocadherin beta 2
  • Synonyms
    PCDH-BETA2
  • Links
    NCBI Gene ID: 56133
    neXtProt AC: NX_Q9Y5E7
    UniProt: Q9Y5E7

  • Chr Location
    5q31.3; chr5:141094606-141098703 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93873 NCBI Gene Model | MGI Sequence Detail 2775 C57BL/6J ±  kb
transcript NM_053127 RefSeq | MGI Sequence Detail 2789 C57BL/6  
polypeptide NP_444357 RefSeq | MGI Sequence Detail 799 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory