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Spock3 Gene Detail
Summary
  • Symbol
    Spock3
  • Name
    sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
  • Synonyms
    2900045C01Rik, testican 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920152
    NCBI Gene: 72902
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:63404043-63810137 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 31.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12255 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920152
 protein coding gene Chr8:63404034-63810137 (+)
129S1/SvImJ ENSMUSG00200007132
 protein coding gene Chr8:58232531-58638573 (+)
A/J ENSMUSG00195011921
 protein coding gene Chr8:58582438-58981900 (+)
AKR/J ENSMUSG00220005134
 protein coding gene Chr8:58403954-58804472 (+)
BALB/cJ ENSMUSG00180013854
 protein coding gene Chr8:58197060-58597566 (+)
C3H/HeJ ENSMUSG00175007394
 protein coding gene Chr8:58422190-58822661 (+)
C57BL/6NJ ENSMUSG00215007209
 protein coding gene Chr8:58225738-58632046 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031082
 protein coding gene Chr8:55374306-55748153 (+)
CAST/EiJ ENSTCUG00005006515
 protein coding gene Chr8:58066316-58469488 (+)
CBA/J ENSMUSG00210008835
 protein coding gene Chr8:58303229-58703687 (+)
DBA/2J ENSMUSG00185022028
 protein coding gene Chr8:64356582-64757100 (+)
FVB/NJ ENSMUSG00205011326
 protein coding gene Chr8:57625652-58046246 (+)
JF1/MsJ ENSUMUG00000007800
 protein coding gene Chr8:66647204-67047526 (+)
LP/J ENSMUSG00230005553
 protein coding gene Chr8:68014665-68415560 (+)
NOD/ShiLtJ ENSMUSG00190009734
 protein coding gene Chr8:58185690-58585114 (+)
NZO/HlLtJ ENSMUSG00225045584
 protein coding gene Chr8:71453925-71867645 (+)
PWK/PhJ ENSLUMG00010012810
 protein coding gene Chr8:58119889-58527312 (+)
SPRET/EiJ ENSMSPG00010014498
 protein coding gene Chr8:59323511-59738328 (+)
WSB/EiJ ENSIUOG00005016797
 protein coding gene Chr8:59136068-59542519 (+)



Homology
more
  • Human Ortholog
    SPOCK3, SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPOCK3, SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
  • Synonyms
    HSAJ1454, TES-3, TICN3
  • Links
    NCBI Gene ID: 50859
    UniProt: Q9BQ16

  • Chr Location
    4q32.3; chr4:166733384-167234945 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotypes from multigenic genotypes
    9 phenotype references
Mice homozygous for a knock-out allele exhibit no obvious morphological or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    652
  • Tissues
    41
  • cDNA Data
    19
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054162 Ensembl Gene Model | MGI Sequence Detail 406095 C57BL/6J ±  kb
transcript ENSMUST00000119068 Ensembl | MGI Sequence Detail 3201 Not Applicable  
polypeptide ENSMUSP00000112930 Ensembl | MGI Sequence Detail 436 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142535
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:224418 Iozzo RV, et al., Proteoglycan form and function: A comprehensive nomenclature of proteoglycans. Matrix Biol. 2015 Mar;42:11-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory